Journal ArticleDOI
Hemostatic Resuscitation in Children.
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TLDR
The following selection of important publications address the current state of hemostatic resuscitation strategies in pediatric trauma patients as well as the remaining knowledge gaps and areas for further research.About:
This article is published in Transfusion Medicine Reviews.The article was published on 2021-08-26. It has received 2 citations till now. The article focuses on the topics: Resuscitation & Tranexamic acid.read more
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Mise au point sur la prise en charge des urgences orthopédiques pédiatriques
TL;DR: In this article , a review of the general rules of paediatric anaesthesia practice for paediatric orthopaedic emergency anaesthesia management before specifying the different modalities specific to each case is presented.
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Augmented Degradation of Factors VIII and IX in the Intermittent Movement State
TL;DR: In this paper , the authors explored whether this phenomenon could be associated with an impact on factor VIII and IX levels in a mouse model using coagulation assays, Western blot analysis and immuno-staining.
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Journal ArticleDOI
Defining massive transfusion in civilian pediatric trauma
Eric H. Rosenfeld,Patricio E. Lau,Wei Zhang,Robert T. Russell,Sohail R. Shah,Bindi Naik-Mathuria,Adam M. Vogel +6 more
TL;DR: An MTP threshold of 37 mL/kg/4 h of transfused blood products predicted the need for hemorrhage control procedures and early mortality and may provide clinicians with a timely prognostic indicator, improve research methodology, and resource utilization.
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Whole-Blood Resuscitation of Injured Patients: Innovating from the Past
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An evaluation of methods for producing low-titer group O whole blood to support military trauma resuscitation.
Tamara R. Belin,Mark H. Yazer,Michael A. Meledeo,Roland L. Fahie,Wilbur W. Malloy,James R. Stubbs,Andrew P. Cap +6 more
TL;DR: Having the capability to collect and transfuse whole blood (WB) has supplemented the lack of PLT availability in austere locations, and the concept of damage control resuscitation, transfusing PRBCs, FFP, and PLTs in balanced ( 1:1:1) ratios early in resuscitate, essentially attempts to recapitulate WB.
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Changes in donor antibody titer levels over time in a military group O low-titer whole blood program.
Jonathan D Bailey,Andrew D Fisher,Mark H. Yazer,Jeffrey T. Howard,Jason B. Corley,Ethan A. Miles,Andrew P. Cap +6 more
TL;DR: Titer testing in a large series of donors is described, demonstrating the ability to rapidly administer whole blood at the point of injury using low titer group O WB donors.
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Whole Blood, Fixed Ratio, or Goal-Directed Blood Component Therapy for the Initial Resuscitation of Severely Hemorrhaging Trauma Patients: A Narrative Review.
Mark Walsh,Ernest E. Moore,Hunter B. Moore,Scott Thomas,Hau C. Kwaan,Jacob Speybroeck,Mathew Marsee,Connor M. Bunch,John E. Stillson,Anthony V. Thomas,Annie Grisoli,John Aversa,Daniel H. Fulkerson,Stefani Vande Lune,Lucas Sjeklocha,Quincy K. Tran +15 more
TL;DR: A physiologically driven and goal-directed alternative to fixed ratio and whole blood, whereby viscoelastic testing guides the administration of blood components and factor concentrates to the severely bleeding trauma patient is detailed.