Heterocyclische o‐Amino‐phosphonester

TLDR: In this paper, the thioacyl-cyanomethane-diethylphosphonate thioenolethers with hydrazines leads to the o-amino-pyrazole-phosphonic esters 2 and 3, with hydroxylamine to the O-aminoisoxazolephosphoric esters 5 and with amidines to O-mino-pyrimidine-phophosphonic eters 6.

Abstract: Die Thioenolather 1 der Thioacyl-cyanmethanphosphonsaure-diathylester kondensieren mit Hydrazinen zu den o-Amino-pyrazol-phosphonestern 2 und 3, mit Hydroxylamin zu den o-Amino-isoxazol-phosphonestern 5 und mit Amidinen zu den o-Amino-pyrimidin-phosphonestern 6. Die Alkalisalze 7 der Thioacyl-cyanmethanphosphonsaure-diathylester cyclisieren mit α-Halogencarbonsaurederivaten zu den o-Amino-thiophen-phosphonestern 8 und mit Chloramin zu den o-Amino-isothiazol-phosphonestern 9. Heterocyclic o-Amino-phosphonic Esters. Condensation of the thioacyl-cyanomethane-diethylphosphonate thioenolethers 1 with hydrazines leads to the o-amino-pyrazole-phosphonic esters 2 and 3, with hydroxylamine to the o-aminoisoxazole-phosphonic esters 5 and with amidines to the o-amino-pyrimidine-phosphonic esters 6. The alkali salts 7 of the thioacyl-cyanomethane-diethylphosphonates cyclize with α-halogencarboxylic acid derivatives to yield the o-amino-thiophene-phosphonic esters 8 and with chloramine to form the o-amino-isothiazole-phosphonic esters 9.