Journal ArticleDOI
Highly chemoselective addition of amines to epoxides in water.
Najmodin Azizi,Mohammad R. Saidi +1 more
TLDR
Beta-amino alcohols were formed under mild conditions with high selectivity and in excellent yields byminolysis of a variety of epoxides by aliphatic and aromatic amines in water.About:
This article is published in Organic Letters.The article was published on 2005-07-28. It has received 268 citations till now. The article focuses on the topics: Aminolysis.read more
Citations
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Organic Synthesis “On Water”
Arani Chanda,Valery V. Fokin +1 more
TL;DR: The currently burgeoning field of organic synthesis in aqueous media encompasses a large family of reactions, and water is still not commonly used as a sole solvent for organic synthesis, at least in part because most organic compounds do not dissolve in water to a significant extent.
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Water: Nature’s Reaction Enforcer—Comparative Effects for Organic Synthesis “In-Water” and “On-Water”
TL;DR: This work presents a meta-analysis of cycloaddition, which aims to determine the carrier and removal status of H2O through a number of mechanisms, including “catalyzed” and “pericyclic” reactions.
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Green chemistry oriented organic synthesis in water
Marc‐Olivier Simon,Chao-Jun Li +1 more
TL;DR: This tutorial review briefly discusses organic synthesis in water with a Green Chemistry perspective.
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Benign by design: catalyst-free in-water, on-water green chemical methodologies in organic synthesis
TL;DR: Various named reactions, multi-component reactions and the synthesis of heterocyclic compounds are discussed including the use of various energy input systems such as microwave- and ultrasound irradiation, among others.
Journal ArticleDOI
Designing the nanoparticle–biomolecule interface for “targeting and therapeutic delivery”
TL;DR: To transfer the remarkable possibilities of nanoscale interactions in biology into therapeutics one may need a more focused and dedicated approach to the understanding of the in situ (in vivo) interface between engineered nanomaedicines and their targets.
References
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1,2-Amino Alcohols and Their Heterocyclic Derivatives as Chiral Auxiliaries in Asymmetric Synthesis
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Catalytic Asymmetric Aminohydroxylation (AA) of Olefins
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The synthetic methodology of nonracemic glycidol and related 2,3-epoxy alcohols
TL;DR: Berch et al. as mentioned in this paper presented a Synthetic Methodology of Nonra cemic Glycidol and Related 2,3-Epoxy Alcohols, Chemi cal Reviews, vol. 91, No. 4, (Jun. 1991) pp. 437-475.
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Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent beta-adrenergic agonist virtually specific for beta 3 receptors. A promising antidiabetic and antiobesity agent.
Jonathan D. Bloom,Minu Dutia,Bernard Dean Johnson,Allan Wissner,Michael G. Burns,Elwood Largis,Jo Alene Dolan,Thomas H. Claus +7 more