Journal ArticleDOI
HIV and metabolic syndrome: a comparison with the general population.
Paolo Bonfanti,Cristina Giannattasio,Elena Ricci,Rita Facchetti,Elena Rosella,M. Franzetti,Laura Cordier,Luigi Pusterla,Michele Bombelli,Roberto Sega,Tiziana Quirino,Giuseppe Mancia +11 more
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TLDR
The risk of MS is greater in HIV-infected patients compared with the general population because of a greater prevalence of lipid and glucose abnormalities.Abstract:
Objective: To compare the prevalence of metabolic syndrome (MS) in HIV-positive patients with that from a sample of a general Italian population. Design: Cross-sectional study. Methods: A total of 1263 HIV-infected patients 18 years of age or older were recruited in 18 centers for infectious diseases in northern and central Italy. Controls were 2051 subjects aged 25 to 74 years representative of the residents of Monza, a town in Milan province, who were enrolled in the Pressioni Arteriose Monitorate E Loro Associazioni study. Results: The prevalence of MS in the HIV group was 20.8%, whereas in the control group, it was only 15.8%, with the difference being statistically significant. The age- and gender-adjusted risk of having MS in HIV-infected patients was twice as great as that in controls. Compared with controls, HIV-infected patients had a greater prevalence of the impaired fasting glucose, increased plasma triglycerides, and reduced high-density lipoprotein cholesterol components. MS prevalence was similar in treated and never-treated HIV-infected patients, and so were the various MS components. Conclusions: The risk of MS is greater in HIV-infected patients compared with the general population because of a greater prevalence of lipid and glucose abnormalities. The prevalence of MS and its components is similar in treated and untreated HIV-positive patients.read more
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Journal ArticleDOI
HIV infection in the elderly
Nancy N. Nguyen,Mark Holodniy +1 more
TL;DR: Clinicians need to be aware of trends and become familiar with the management of HIV infection in the older patient as treated HIV-infected patients live longer and the number of new HIV diagnoses in older patients rise.
Journal ArticleDOI
A Meta-Analysis of the Metabolic Syndrome Prevalence in the Global HIV-Infected Population
Kim A. Nguyen,Kim A. Nguyen,Nasheeta Peer,Nasheeta Peer,Edward J Mills,Andre Pascal Kengne,Andre Pascal Kengne +6 more
TL;DR: The similar range of MS prevalence in the HIV-infected and general populations highlights the common drivers of this condition.
Journal ArticleDOI
The aging of the HIV epidemic
TL;DR: This review addresses many of the important considerations to meet the challenges of the ongoing HIV epidemic, and addresses how the processes of aging and HIV infection overlap and interact.
Journal ArticleDOI
Aortic stiffness in untreated adult patients with human immunodeficiency virus infection.
Giuseppe Schillaci,Giuseppe Vittorio De Socio,Giacomo Pucci,Massimo Raffaele Mannarino,J. Helou,Matteo Pirro,Elmo Mannarino +6 more
TL;DR: In this paper, the authors investigated whether aortic stiffness, an early marker of arteriosclerosis, is increased in HIV patients who were not under antiretroviral treatment.
Journal ArticleDOI
High prevalence of the metabolic syndrome in HIV-infected patients: impact of different definitions of the metabolic syndrome.
Signe Westring Worm,Nina Friis-Møller,Mathias Bruyand,Antonella dʼArminio Monforte,Martin Rickenbach,Peter Reiss,Wafaa El-Sadr,Andrew N. Phillips,Jens D Lundgren,Caroline A. Sabin +9 more
TL;DR: It is suggested that the prevalence of the metabolic syndrome in cohort studies should be based on two consecutive measurements of the laboratory components in the syndrome definition, largely based on the use of nonstandardized measurements as they are captured in daily clinical care.
References
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