Tiziana Quirino

TL;DR: No associations with mortality were found with any circulating miRNAs studied and these results cast doubt onto the effectiveness of circulating miRNA as early predictors of mortality or the major underlying diseases that contribute to mortality in participants treated for HIV-1 infection.

TL;DR: Results show that impairment of the gastrointestinal tracts in human immunodeficiency virus (HIV)-positive patients is present in the early phases of HIV disease, and this impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters.

TL;DR: Dietary supplementation with a prebiotic oligosaccharide mixture results in improvement of the gut microbiota composition, reduction of sCD14, CD4+ T-cell activation (CD25), and improved NK cell activity in HAART-naive HIV-infected individuals.

TL;DR: In the study population, CMV/HIV coinfection was associated with the risk of severe non-AIDS-defining events/non- AIDS-related death, especially with cardiovascular and cerebrovascular events, independently of other prognostic factors.

TL;DR: Ritonavir is the drug associated with the largest number of reactions, which appear during the first few months of treatment, and Saquinavir HGC and nelfinavir are the best tolerated drugs in a clinical setting.