Journal ArticleDOI
Identification of the enantioselective step in the asymmetric catalytic hydrogenation of a prochiral olefin
About:
This article is published in Journal of the American Chemical Society.The article was published on 1980-08-01. It has received 239 citations till now. The article focuses on the topics: Enantioselective synthesis & Olefin fiber.read more
Citations
More filters
Journal ArticleDOI
Asymmetric Transition Metal-Catalyzed Allylic Alkylations.
TL;DR: The focus of this review is on the area of enantioselective transition metal-catalyzed allylic alkylations which may involve C-C as well as C-X (X ) H or heteroatom) bond formation.
Journal ArticleDOI
New Chiral Phosphorus Ligands for Enantioselective Hydrogenation
Wenjun Tang,Xumu Zhang +1 more
TL;DR: The increasing demand to produce enantiomerically pure pharmaceuticals, agrochemicals, flavors, and other fine chemicals has advanced the field of asymmetric catalytic technologies, and asymmetric hydrogenation utilizing molecular hydrogen to reduce prochiral olefins, ketones, and imines has become one of the most efficient methods for constructing chiral compounds.
Journal ArticleDOI
Homogeneous catalysis by transition metal oxygen anion clusters
TL;DR: In this paper, a thorough discussion of homogeneous catalysis by transition metal oxygen anion clusters (polyoxometalates), with a focus on mechanism, is provided, and a general compilation of the reactions, including catalytic electrooxidations or electroreductions, reported to date is given.
Journal ArticleDOI
Double Asymmetric Synthesis and a New Strategy for Stereochemical Control in Organic Synthesis
TL;DR: In this article, it is shown that double asymmetric induction can be analyzed in terms of the single asymmetric reactions of each of the two chiral reactants, and a new strategy based on this rule for the predictable creation of new chiral centers is discussed and the use of this strategy for the synthesis of sugars and macrolides is presented.
Journal ArticleDOI
Mechanism and stereoselectivity of asymmetric hydrogenation.
TL;DR: It is concluded that the stereoselection is dictated not by the preferred initial binding of the substrate to the chiral catalyst, but rather by the much higher reactivity of the minor diastereomer of the catalyst-substrate adduct corresponding to the less favored binding mode.
Related Papers (5)
Asymmetric hydrogenation of methyl (Z)-.alpha.-acetamidocinnamate catalyzed by [1,2-bis(phenyl-o-anisoyl)phosphino)ethane]rhodium(I): kinetics, mechanism and origin of enantioselection
Clark R. Landis,Jack Halpern +1 more
Interception and characterization of a hydridoalkylrhodium intermediate in a homogeneous catalytic hydrogenation reaction
Albert S. C. Chan,Jack Halpern +1 more