Journal ArticleDOI
Immunoaffinity in-tube solid phase microextraction coupled with liquid chromatography-mass spectrometry for analysis of fluoxetine in serum samples.
TLDR
It was demonstrated that in-tube SPME/LC-MS method offers high sensitivity, selectivity, and enough reproducibility to permit the quantification of fluoxetine in human serum at therapeutic levels, and can be useful tool to determine fluoxettine serum concentrations in patients receiving therapeutic dosages.About:
This article is published in Journal of Chromatography A.The article was published on 2007-12-07. It has received 84 citations till now. The article focuses on the topics: Solid-phase microextraction & Blood serum.read more
Citations
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Journal ArticleDOI
A review of current trends and advances in modern bio-analytical methods: chromatography and sample preparation.
Lucie Nováková,Hana Vlčková +1 more
TL;DR: UHPLC has recently become a wide-spread analytical technique in many laboratories which focus on fast and sensitive bio-analytical assays and the key advantages are the increased speed of analysis, higher separation efficiency and resolution, higher sensitivity and much lower solvent consumption as compared to other analytical approaches.
Journal ArticleDOI
Nondestructive sampling of living systems using in vivo solid-phase microextraction.
TL;DR: Nondestructive Sampling of Living Systems Using in Vivo Solid-Phase Microextraction Gangfeng Ouyang, Dajana Vuckovic, and Janusz Pawliszyn.
Journal ArticleDOI
Critical review on recent developments in solventless techniques for extraction of analytes
TL;DR: The most recent contributions on solventless extraction techniques have been reviewed and direct extraction and derivatization processes to facilitate the extraction of analytes in different areas have been included.
Journal ArticleDOI
A critical review of the state of the art of solid-phase microextraction of complex matrices III. Bioanalytical and clinical applications
Érica A. Souza-Silva,Nathaly Reyes-Garcés,Germán Augusto Gómez-Ríos,Ezel Boyacı,Barbara Bojko,Barbara Bojko,Janusz Pawliszyn +6 more
TL;DR: In this article, a review of the state of the art of solid-phase microextraction (SPME) applied to bioanalytical and clinical analysis is presented, with a discussion on the advantages and disadvantages of SPME related to the analysis of these biological matrices.
Journal ArticleDOI
Recent advances in SPME techniques in biomedical analysis
Hiroyuki Kataoka,Keita Saito +1 more
TL;DR: This review focuses on recent advances in novel SPME techniques, including fiber S PME and in-tube SPMe, in biomedical analysis and summarizes the applications of these techniques to pharmacotherapeutic, forensic, and diagnostic studies, and to determinations of environmental and occupational exposure.
References
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Journal ArticleDOI
Microextraction of drugs
Heather L. Lord,Janusz Pawliszyn +1 more
TL;DR: This review will attempt to provide an overview as well as a theoretical and practical understanding of the use of microextraction technologies for drug analysis, with particular emphasis on the effect various sample matrices have on extraction characteristics.
Journal ArticleDOI
Clinically relevant pharmacology of selective serotonin reuptake inhibitors. An overview with emphasis on pharmacokinetics and effects on oxidative drug metabolism.
TL;DR: An overview of the clinically relevant pharmacology of selective serotonin reuptake inhibitors (SSRIs) with an emphasis on their pharmacokinetics and effects on cytochrome P450 (CYP) enzymes is presented.
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Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.
H Kirchherr,W N Kühn-Velten +1 more
TL;DR: This method describes the simultaneous determination of amisulpride, amitriptyline, aripiprazole, benperidol, chlorpromazine, chlorprothixene, citalopram, clomipramine, clozapine, desipramines, doxepin, fluoxetine, flupentixol, fl uphenazine, fluvoxamine, haloperidol
Journal ArticleDOI
Clinical Pharmacokinetics of Fluoxetine
TL;DR: There appears to be a therapeutic window for fluoxetine, and the pharmacokinetics of this drug are not affected by either obesity or renal impairment, which makes this drug particularly suitable for use in elderly patients with depression.
Journal ArticleDOI
Automated sample preparation using in-tube solid-phase microextraction and its application – a review
TL;DR: An overview of the development of in-tube SPME technique and its applications to environmental, clinical, forensic, and food analyses are described.