Impact of preconditioning protocol on anesthetic-induced cardioprotection in patients having coronary artery bypass surgery
Jan Frässdorf,Andreas Borowski,D. Ebel,Peter Feindt,Manuel Hermes,Thomas Meemann,Rene Weber,Jost Müllenheim,Nina C. Weber,Benedikt Preckel,Benedikt Preckel,Wolfgang Schlack +11 more
TLDR
Data show that sevoflurane-induced preconditionsing is reproducible in patients having coronary artery bypass but depends on the preconditioning protocol used.About:
This article is published in The Journal of Thoracic and Cardiovascular Surgery.The article was published on 2009-06-01 and is currently open access. It has received 81 citations till now. The article focuses on the topics: Coronary artery bypass surgery & Ischemic preconditioning.read more
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Effects of volatile anesthetics on mortality and postoperative pulmonary and other complications in patients undergoing surgery: a systematic review and meta-analysis
Christopher Uhlig,Thomas Bluth,Kristin Schwarz,Stefanie Deckert,L Heinrich,Stefan De Hert,Giovanni Landoni,Ary Serpa Neto,Marcus J. Schultz,Paolo Pelosi,Jochen Schmitt,Marcelo Gama de Abreu +11 more
TL;DR: In cardiac, but not in noncardiac, surgery, when compared to total IV anesthesia, general anesthesia with volatile anesthetics was associated with major benefits in outcome, including reduced mortality, as well as lower incidence of pulmonary and other complications.
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A comparison of volatile and non volatile agents for cardioprotection during on-pump coronary surgery
S. G. De Hert,Dirk Vlasselaers,R. Barbé,J-P. Ory,D. Dekegel,R. Donnadonni,J-L. Demeere,Jan Paul Mulier,Patrick Wouters +8 more
TL;DR: A randomised study of 414 patients undergoing coronary artery surgery with cardiopulmonary bypass to compare the effects of a volatile anaesthetic regimen with either deesflurane or sevoflurane, and a total intravenous anaesthesia (TIVA) regimen on postoperative troponin T release.
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Anaesthesia and myocardial ischaemia/reperfusion injury
TL;DR: This review will focus on the translation of the laboratory evidence of anaesthetic-induced cardioprotection into daily clinical practice.
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β-blockers and volatile anesthetics may attenuate cardioprotection by remote preconditioning in adult cardiac surgery: a meta-analysis of 15 randomized trials.
TL;DR: The cardioprotective effect may be attenuated when combined with β-blockers or volatile anesthetics, and available data from this meta-analysis further confirmed theCardioprotection conferred by RIPC in adult cardiac surgery.
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Peri-operative anaesthetic myocardial preconditioning and protection – cellular mechanisms and clinical relevance in cardiac anaesthesia
Gudrun Kunst,Andrew A. Klein +1 more
TL;DR: This review summarises experimentally proposed mechanisms of anaesthetic preconditioning, and assesses randomised controlled clinical trials in cardiac anaesthesia that have been aimed at translating experimental results into the clinical setting.
References
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Journal ArticleDOI
Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium.
TL;DR: The multiple anginal episodes that often precede myocardial infarction in man may delay cell death after coronary occlusion, and thereby allow for greater salvage of myocardium through reperfusion therapy, which is proposed to protect the heart from a subsequent sustained ischemic insult.
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Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction.
Elliott M. Antman,Jean-Pierre Bassand,Werner Klein,Magnus Ohman,José Luis López Sendón,Lars Rydén,Maarten L. Simoons,Michal Tendera +7 more
TL;DR: In this paper, the authors defined the definition of MI and established the following criteria for acute, evolving or recent MI: 1) Typical rise and gradual fall (troponin) or more rapid rise and fall (CK-MB) of biochemical markers of myocardial necrosis with at least one of the following: a) ischemic symptoms; b) development of pathologic Qwaves on the ECG; c) ECG changes indicative of ischemia (ST segment elevation or depression); or d) coronary artery intervention (e.g., coronary ang
Journal ArticleDOI
Myocardial infarction redefined - A consensus document of the Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarction
Joseph S. Alpert,Elliott M. Antman,Fred S. Apple,Paul W. Armstrong,J. P. Bassand,A. B. De Luna,George A. Beller,Günter Breithardt,Bernard R. Chaitman,Peter Clemmensen,Erling Falk,Michael C. Fishbein,Marcello Galvani,A Jr Garson,Cindy L. Grines,Christian W. Hamm,B. Nauheim,Uta C. Hoppe,Allan S. Jaffe,Hugo A. Katus,J. Kjeksus,Werner Klein,P. Klootwijk,C. Lenfant,Daniel Levy,R. I. Levy,Russell V. Luepker,F. Marcus,Ulf Näslund,Magnus Ohman,O. Pahlm,P. A. Poole-Wilson,R. Popp,Kalevi Pyörälä,Jan Ravkilde,N. Rehnquist,W. Roberts,Robert Roberts,J. Roelandt,Lars Rydén,Susana Sans,M. L. Simoons,Kristian Thygesen,Hugh Tunstall-Pedoe,Richard Underwood,Barry F. Uretsky,F. Van de Werf,L. M. Voipio-Pulkki,Galen S. Wagner,Lars Wallentin,William Wijns,David R. Wood +51 more
TL;DR: Biochemical markers of myocardial necrosis may have normalized, depending on the length of time that has passed since the infarct developed, and one of the following criteria satisfies the diagnosis for established MI: development of new pathologic Q waves on serial ECGs.
Journal Article
Erratum: Myocardial infarction redefined - A consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction (Journal of the American College of Cardiology (2000) 36 (959-969))
Journal ArticleDOI
Cardioprotective properties of sevoflurane in patients undergoing coronary surgery with cardiopulmonary bypass are related to the modalities of its administration
Stefan De Hert,Philippe Van der Linden,Stefanie Cromheecke,R. Meeus,Anne Nelis,Veronique Van Reeth,Pieter W. ten Broecke,Ivo I.G. De Blier,Bernard Stockman,I E Rodrigus +9 more
TL;DR: In patients undergoing coronary artery surgery with cardiopulmonary bypass, the cardioprotective effects of sevoflurane were clinically most apparent when it was administered throughout the operation.