Journal ArticleDOI
Interactions between cutaneous afferent inputs to a withdrawal reflex in the decerebrated rabbit and their control by descending and segmental systems.
TLDR
Activity in fine afferent axons augments the reflexogenic potential of all subsequent afferent input, thereby allowing all afferent drive from the sural field to contribute to withdrawal of the heel.About:
This article is published in Neuroscience.The article was published on 2002-07-05. It has received 46 citations till now. The article focuses on the topics: Reflex & Withdrawal reflex.read more
Citations
More filters
Journal ArticleDOI
The lower limb flexion reflex in humans.
Giorgio Sandrini,Mariano Serrao,Paolo Giorgi Rossi,Antonietta Romaniello,Giorgio Cruccu,Jean-Claude Willer +5 more
TL;DR: Study of the LLFR in humans has proved to be an interesting functional window onto the spinal and supraspinal mechanisms of pain processing and on the spinal neural control mechanisms operating during posture and locomotion.
Journal ArticleDOI
Persistent inward currents in motoneuron dendrites: implications for motor output
TL;DR: The brainstem neuromodulatory input provides a mechanism by which the excitability of motoneurons can be varied for different motor behaviors, which is lost in spinal cord injury but PICs nonetheless recover near‐normal amplitudes in the months following the initial injury.
Journal ArticleDOI
Role of Persistent Sodium and Calcium Currents in Motoneuron Firing and Spasticity in Chronic Spinal Rats
TL;DR: Both the calcium and sodium PIC were involved in motoneuron firing because nimodipine only partly reduced the reflex and there remained very slow firing mediated by the calcium PIC.
Journal ArticleDOI
Management of Spasticity After Spinal Cord Injury: Current Techniques and Future Directions
TL;DR: Critical assessment of experimental findings indicates that increased excitability of both motoneurons and interneurons plays a crucial role in pathophysiology of spasticity and new interventions, including forms of spinal electrical stimulation to suppress increased neuronal excitability, may reduce the severity of spasticsity and its complications.
Journal ArticleDOI
Spastic long-lasting reflexes in the awake rat after sacral spinal cord injury.
TL;DR: There is an unusually long low-threshold polysynaptic input to the motoneurons (pEPSP) that is normally inhibited by descending control that triggers sustained motoneuron discharges associated with long-lasting reflexes and muscle spasms with chronic injury.
References
More filters
Journal ArticleDOI
Physiological Properties of Unmyelinated Fiber Projection to the Spinal Cord
TL;DR: It was suggested that the C fiber input produced the increase in dynamic range and that this accounted for the involvement of unmyelinated fibers in high threshold phenomena (e.g., pain).
Journal ArticleDOI
Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following c fibre stimulation.
TL;DR: The results suggest an involvement of the NMDA receptor in this potentiation of dorsal horn nociceptive neurones in the intact halothane anaesthetized rat.
Journal ArticleDOI
Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans.
TL;DR: In this paper, Capsaicin, the algesic substance in chilli peppers, was injected intradermally in healthy human subjects, and the results indicated that hyperalgesia to stroking on a skin area surrounding a painful intradermal injection of capsaicin is due to reversible changes in the central processing of mechanoreceptive input from myelinated fibres which normally evoke non-painful tactile sensations.
Journal ArticleDOI
Evidence for involvement of N-methylaspartate receptors in 'wind-up' of class 2 neurones in the dorsal horn of the rat
Stephen N. Davies,David Lodge +1 more
TL;DR: N-Methylaspartate receptors appear to contribute to the wind-up, but not the initial response, of class 2 neurones in the rat, while Iontophoretic or intravenous ketamine had no consistent effect on theInitial response but consistently reduced wind- up.
Related Papers (5)
Persistent Sodium and Calcium Currents Cause Plateau Potentials in Motoneurons of Chronic Spinal Rats
Y. Li,David J. Bennett +1 more