Journal ArticleDOI
Iron and copper chelation by flavonoids: an electrospray mass spectrometry study.
TLDR
Electrospray mass spectrometry has been used to study metal ion interactions with a set of flavonoids from different classes, establishing for flavones and for the flavanone naringenin that the binding metal sites are preferentially at the 5-hydroxyl and 4-oxo groups.About:
This article is published in Journal of Inorganic Biochemistry.The article was published on 2002-11-11. It has received 294 citations till now. The article focuses on the topics: Flavanone & Redox.read more
Citations
More filters
Journal ArticleDOI
Natural antioxidants: sources, compounds, mechanisms of action, and potential applications
TL;DR: An overview of natural antioxidants, their mechanisms of action, and potential applications can be found in this article, where the authors provide an overview of the potential applications of these natural antioxidants.
Journal ArticleDOI
The molecular basis of working mechanism of natural polyphenolic antioxidants
TL;DR: In this article, a summary of the research work performed so far using high accuracy quantum chemical methods on polyphenolic antioxidant compounds is presented, which represents a further important contribution to elucidation of the beneficial effects on health of these substances.
Journal ArticleDOI
Iron Chelation by the Powerful Antioxidant Flavonoid Quercetin
TL;DR: Chelation of the bare and hydrated iron(II) cation by quercetin has been investigated at the DF/B3LYP level in the gas phase and results indicate that among the potential sites of chelation present on quercettin, the oxygen atoms belonging to the 3-hydroxy and 4-oxo, and to the 5-hydroxyl groups, are the preferred ones.
Journal ArticleDOI
Electrospray mass spectrometry (ESI-MS) in the study of metal-ligand solution equilibria.
TL;DR: The application of ESI-MS to the study of metal-ligand solution equilibria and related applications, such as host-guest interactions and metal ion-protein binding studies, are briefly reviewed.
Journal ArticleDOI
Phenol-Based Antioxidants and the In Vitro Methods Used for Their Assessment
TL;DR: A review of the chemistry behind the antioxidant activity of phenolics can be found in this article, which summarizes the many methods applicable for the measurement of in vitro phenolic antioxidant capacity.
References
More filters
Book
Free radicals in biology and medicine
TL;DR: 1. Oxygen is a toxic gas - an introduction to oxygen toxicity and reactive species, and the chemistry of free radicals and related 'reactive species'
Journal ArticleDOI
The Free Radical Theory of Aging Matures
Kenneth B. Beckman,Bruce N. Ames +1 more
TL;DR: The status of the free radical theory of aging is reviewed, by categorizing the literature in terms of the various types of experiments that have been performed, which include phenomenological measurements of age-associated oxidative stress, interspecies comparisons, dietary restriction, and the ongoing elucidation of the role of active oxygen in biology.
Journal ArticleDOI
Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships.
TL;DR: The antioxidant and prooxidant behavior of flavonoids and the related activity-structure relationships were investigated in this study using the oxygen radical absorbance capacity assay.
Book
Techniques of flavonoid identification.
TL;DR: This book presents a more extensive, up-to-date and thorough guide to techniques used in flavonoid research, and discusses examples of a wide range of spectra, and features diagrams of flavonoids structures, reaction schemes and apparatus.
Journal ArticleDOI
Free radicals, oxidative stress, and antioxidants in human health and disease
TL;DR: Assessment of oxidativedamage to biomolecules by means of emerging technologies based on products of oxidative damage to DNA, lipids, and proteins would not only advance the understanding of the underlying mechanisms but also facilitate supplementation and intervention studies designed and conducted to test antioxidant efficacy in human health and disease.