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Is there any difference between blood and crystalloid cardioplegia for myocardial protection during cardiac surgery? A meta-analysis of 5576 patients from 36 randomized trials

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TLDR
Evidence is found that argues against any superiority in terms of hard outcomes between blood or crystalloid cardioplegia for myocardial protection during cardiac surgery.
Abstract
Objective:To compare the efficacy of blood versus crystalloid cardioplegia for myocardial protection in patients undergoing cardiac surgery.Methods:MEDLINE, EMBASE, CENTRAL/CCTR, SciELO, LILACS, Go...

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Coronary artery bypass grafting: Part 1--the evolution over the first 50 years.

TL;DR: This review provides a historical recapitulation of experimental surgery, the evolution of the surgical techniques and the utilization of CABG, and data on contemporary clinical outcomes are discussed.
Journal ArticleDOI

The Use of del Nido Cardioplegia in Adult Cardiac Surgery: A Prospective Randomized Trial

TL;DR: Evidence from this study suggests del Nido cardioplegia use in routine adult cases may be safe, result in comparable clinical outcomes, and streamline surgical workflow.
Journal ArticleDOI

Propensity Matched Analysis of del Nido Cardioplegia in Adult Coronary Artery Bypass Grafting: Initial Experience With 100 Consecutive Patients.

TL;DR: In the initial experience, DC provided equivalent myocardial protection and clinical outcomes to BC in adult isolated CABG patients and demonstrated the feasibility of single-dose administration for routine coronary operations.
References
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Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Journal ArticleDOI

Measuring inconsistency in meta-analyses

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI

Bias in meta-analysis detected by a simple, graphical test

TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement

TL;DR: A structured summary is provided including, as applicable, background, objectives, data sources, study eligibility criteria, participants, interventions, study appraisal and synthesis methods, results, limitations, conclusions and implications of key findings.
Journal ArticleDOI

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

TL;DR: PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is introduced, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses.
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