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Isolation and identification of prostaglandins from human seminal plasma. 18. prostaglandins and related factors.

Bengt Samuelsson
- 01 Oct 1963 - 
- Vol. 238, Iss: 10, pp 3229-3234
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This article is published in Journal of Biological Chemistry.The article was published on 1963-10-01 and is currently open access. It has received 198 citations till now.

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Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition

TL;DR: Characterization of the two COX isozymes is allowing the discrimination of the roles each play in physiological processes such as homeostatic maintenance of the gastrointestinal tract, renal function, blood clotting, embryonic implantation, parturition, pain, and fever.
Journal ArticleDOI

Prostaglandins and thromboxanes.

TL;DR: This chapter discusses major advances in prostaglandin chemistry and biological activity and indicates the extent to which research has progressed towards the realization of earlier hopes of the discovery of new therapeutic agents.
Journal ArticleDOI

Prostaglandins and related factors: xix. thin-layer chromatography of prostaglandins.

TL;DR: In this paper, the authors described methods for separation of all known prostaglandins and some derivatives as free acids and methyl esters by thin-layer chromatography both on analytical and preparative scales.
Journal ArticleDOI

Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology,

TL;DR: In this article, a review of proteins implicated in eicosanoid biosynthesis and signaling in human, mouse, and rat is presented, along with applications of the extensive genomic and lipidomic research to date.
Journal ArticleDOI

The biosynthesis of prostaglandins.

TL;DR: Prostaglandins work to reduce blood pressure, and affect the heart beat, lipolysis, and the workings of the smooth musculature.
References
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On the specific vaso-dilating and plain muscle stimulating substances from accessory genital glands in man and certain animals (prostaglandin and vesiglandin)

TL;DR: Experiments with isolated uterus of various animals showed that prostaglandin enhanced the uterus activity; it has similar action on isolated human uterus and atropine did not abolish these biological actions.
Journal ArticleDOI

Properties of human seminal plasma.

TL;DR: It is suggested that the vasodilator may help maintain local vasodILatation in accessory glands and ducts of the male genital tract and ensure an active gaseous exchange between the blood and various seminal secretions.
Journal ArticleDOI

The structure of prostaglandin E F1 and F2.

TL;DR: In this article, the chemical degradations necessary to elucidate the structure of prostaglandins E F 1 and F 2 were reported, and it was pointed out that most identifications of these compounds have been nonclassical, i.e., by mass spectrometry of fractions isolated by gas chromatography and comparison of the masspectrograms with synthetic compounds.
Journal ArticleDOI

On the transformation and enterohepatic circulation of cholic acid in the rat: bile acids and steroids 68.

TL;DR: The aim of the present investigation was to find out where these transformations take place, and to ascertain the nature of the products formed and whether these products are reabsorbed so as to take part in the enterohepatic circulation.
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