Laboratory Diagnosis of Visceral Leishmaniasis
Shyam Sundar,Madhukar Rai +1 more
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The group of diseases known as the leishmaniases are caused by obligate intracellular protozoa of the genus Leishmania.Abstract:
The group of diseases known as the leishmaniases are caused by obligate intracellular protozoa of the genus Leishmania ([39][1]). Natural transmission of leishmania is carried out by a certain species of sandfly of the genus Phlebotomus (Old World) or Lutzomyia (New World). These are present inread more
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Harrison's Principles of Internal Medicine
TL;DR: The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors.
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Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America.
TL;DR: The most recent version of the guidelines for the prevention and treatment of opportunistic infections (OI) in HIV-infected adults and adolescents was published in 2002 and 2004, respectively as mentioned in this paper.
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Leishmaniose visceral no Brasil: quadro atual, desafios e perspectivas
TL;DR: O artigo foram analisados os principais aspectos biologicos, ambientais e sociais that influenciaram no processo de expansao e urbanizacao dos focos da doenca no Brasil.
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Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents
Jonathan E. Kaplan,Constance A. Benson,King K. Holmes,John T. Brooks,Alice Pau PharmD,Henry Masur +5 more
TL;DR: This report updates and combines earlier versions of guidelines for the prevention and treatment of opportunistic infections in HIV-infected adults and adolescents and adds malaria to the list of OIs that might be acquired during international travel.
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Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial
Shyam Sundar,Prabhat K. Sinha,Madhukar Rai,Deepak Kumar Verma,Kumar Nawin,Shanawwaj Alam,Jaya Chakravarty,Michel Vaillant,Neena Verma,Krishna Pandey,Poonam Kumari,Chandra Shekhar Lal,Rakesh Kumar Arora,Bhawna Sharma,Sally Ellis,Nathalie Strub-Wourgaft,Manica Balasegaram,Piero Olliaro,Pradeep Das,Farrokh Modabber +19 more
TL;DR: Combination treatments for visceral leishmaniasis are efficacious and safe, and decrease the duration of therapy, thereby encouraging adherence and reducing emergence of drug-resistant parasites.
References
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Journal ArticleDOI
Harrison's Principles of Internal Medicine
TL;DR: The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors.
Journal ArticleDOI
The increase in risk factors for leishmaniasis worldwide.
TL;DR: Increasing risk factors are making leishmaniasis a growing public health concern for many countries around the world, and some are related to a specific eco-epidemiological entity, others affect all forms of leish maniasis.
Journal ArticleDOI
Leishmania and human immunodeficiency virus coinfection: the first 10 years.
Jorge Alvar,Carmen Cañavate,Beatriz Gutiérrez-Solar,Maribel Jiménez,Fernando Laguna,Rogelio López-Vélez,Ricardo Molina,Javier Moreno +7 more
TL;DR: Over 850 Leishmania-human immunodeficiency virus (HIV) coinfection cases have been recorded, the majority in Europe, where 7 to 17% of HIV-positive individuals with fever have amastigotes, suggesting that Leishmanniasis-infected individuals without symptoms will express symptoms of leishmaniasis if they become immunosuppressed.
Journal ArticleDOI
Molecular characterization of a kinesin-related antigen of Leishmania chagasi that detects specific antibody in African and American visceral leishmaniasis.
J. M. Burns,Wayne G. Shreffler,Darin R. Benson,Hashim W. Ghalib,Roberto Badaró,Reed Steven G +5 more
TL;DR: The cloning of a Leishmania chagasi antigen gene and an evaluation of leishmaniasis patient antibody responses to the recombinant protein, rK39, show that rK 39 may replace crude parasite antigens as a basis for serological diagnosis of visceral leish maniasis.
Journal ArticleDOI
Mucosal leishmaniasis ("espundia" Escomel, 1911).
TL;DR: One of the more serious clinical forms of leishmaniasis occurs in espundia when the mucosae of the upper respiratory passages are inflamed, and specific treatment targeted to this specific problem is the efficient short term solution.