B
Bhawna Sharma
Researcher at Indian Council of Medical Research
Publications - 32
Citations - 720
Bhawna Sharma is an academic researcher from Indian Council of Medical Research. The author has contributed to research in topics: T cell & Population. The author has an hindex of 12, co-authored 27 publications receiving 616 citations. Previous affiliations of Bhawna Sharma include Drugs for Neglected Diseases Initiative.
Papers
More filters
Journal ArticleDOI
Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial
Shyam Sundar,Prabhat K. Sinha,Madhukar Rai,Deepak Kumar Verma,Kumar Nawin,Shanawwaj Alam,Jaya Chakravarty,Michel Vaillant,Neena Verma,Krishna Pandey,Poonam Kumari,Chandra Shekhar Lal,Rakesh Kumar Arora,Bhawna Sharma,Sally Ellis,Nathalie Strub-Wourgaft,Manica Balasegaram,Piero Olliaro,Pradeep Das,Farrokh Modabber +19 more
TL;DR: Combination treatments for visceral leishmaniasis are efficacious and safe, and decrease the duration of therapy, thereby encouraging adherence and reducing emergence of drug-resistant parasites.
Journal ArticleDOI
Phytofabrication of Silver nanoparticles: Novel Drug to overcome hepatocellular ailments.
TL;DR: In this article, a green synthesized AgNPs showed a promising curing effect on hepatocellular ailments and showed that the elevated levels of Liver Function Test (LFTs) biomarkers were significantly reversed and the antioxidant levels were significantly recouped towards normal after the conjoint treatment of AgNs in a dosedependent manner.
Journal ArticleDOI
Nitroimidazo-oxazole compound DNDI-VL-2098: an orally effective preclinical drug candidate for the treatment of visceral leishmaniasis
Suman Gupta,Vanessa Yardley,Preeti Vishwakarma,Rahul Shivahare,Bhawna Sharma,Delphine Launay,Denis Martin,Sunil K. Puri +7 more
TL;DR: It is revealed that, along with leishmanicidal activity, DNDI-VL-2098 was also capable of inducing host-protective immune cells to suppress Leishmania parasites in hamsters.
Journal ArticleDOI
Safety and efficacy of short course combination regimens with AmBisome, miltefosine and paromomycin for the treatment of visceral leishmaniasis (VL) in Bangladesh
Ridwanur Rahman,Vishal Goyal,Rashidul Haque,Kazi M. Jamil,Abul Faiz,Rasheda Samad,Sally Ellis,Manica Balasegaram,Margriet den Boer,Suman Rijal,Nathalie Strub-Wourgaft,Fabiana Alves,Jorge Alvar,Bhawna Sharma +13 more
TL;DR: None of the combinations were inferior to AmBisome in both the intention-to-treat and per-protocol populations and all the combinations demonstrated excellent overall efficacy, were well tolerated and safe, and could be deployed under field conditions in Bangladesh.
Journal ArticleDOI
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.
M A Adjuik,Richard Allan,Anup Anvikar,Elizabeth A. Ashley,M S Ba,Hubert Barennes,Karen I. Barnes,Quique Bassat,Elisabeth Baudin,Anders Björkman,François Bompart,Maryline Bonnet,Steffen Borrmann,Philippe Brasseur,Hasifa Bukirwa,Francesco Checchi,Michel Cot,Michel Cot,Prabin Dahal,Umberto D'Alessandro,Philippe Deloron,Philippe Deloron,Meghna Desai,G Diap,Abdoulaye Djimde,Grant Dorsey,Ogobara K. Doumbo,E Espié,Etard J-F.,Caterina I. Fanello,Faucher J-F.,Babacar Faye,Jennifer A. Flegg,Gaye O,Peter W. Gething,Raquel González,Francesco Grandesso,Philippe J Guerin,Guthmann J-P.,Sally Hamour,Armedy Ronny Hasugian,Simon I. Hay,Georgina S Humphreys,Vincent Jullien,Elizabeth Juma,Moses R. Kamya,Corine Karema,Jean-René Kiechel,Peter G. Kremsner,Sanjeev Krishna,Valerie Lameyre,L M Ibrahim,Sue J. Lee,Bertrand Lell,Andreas Mårtensson,Achille Massougbodji,Hervé Ei Menan,Didier Menard,Clara Menéndez,Martin M Meremikwu,Clarissa Moreira,Carolyn Nabasumba,Michael Nambozi,Ndiaye J-L.,Frederic Nikiema,Christian Nsanzabana,Francine Ntoumi,Francine Ntoumi,Bernards Ogutu,Piero Olliaro,Lyda Osorio,Ouédraogo J-B.,Louis K. Penali,Mbaye Pene,Loretxu Pinoges,Patrice Piola,Ric N. Price,Cally Roper,Philip J. Rosenthal,Claude Rwagacondo,Albert Same-Ekobo,Birgit Schramm,A Seck,Bhawna Sharma,Carol Hopkins Sibley,Véronique Sinou,Sodiomon B. Sirima,Jeff Smith,Frank Smithuis,Fabrice A. Somé,D Sow,Sarah G. Staedke,Kasia Stepniewska,Todd D. Swarthout,K Sylla,Ambrose O. Talisuna,Joel Tarning,Taylor Wrj.,Taylor Wrj.,E A Temu,E A Temu,Julie Thwing,Emiliana Tjitra,Tine Rck.,Halidou Tinto,Michel Vaillant,Neena Valecha,I Van den Broek,Nicholas J. White,Adoke Yeka,Issaka Zongo +110 more
TL;DR: Fixed dose AS-AQ combinations ensure optimal dosing and provide higher antimalarial treatment efficacy than the loose individual tablets in all age categories.