Journal ArticleDOI
Lack of promoting effects of chronic exposure to 1.95-GHz W-CDMA signals for IMT-2000 cellular system on development of N-ethylnitrosourea-induced central nervous system tumors in F344 rats.
Tomoyuki Shirai,Toshio Ichihara,Kanako Wake,Soichi Watanabe,Yukio Yamanaka,Mayumi Kawabe,Masao Taki,Osamu Fujiwara,Jianqing Wang,Satoru Takahashi,Seiko Tamano +10 more
Reads0
Chats0
TLDR
Exposure of heads of rats to 1.95‐GHz W‐CDMA signals for IMT‐2000 for a 2‐year period was not demonstrated to accelerate or otherwise affect ENU‐initiated brain tumorigenesis, and no clear changes in tumor types in the brain were evident.Abstract:
The present study was performed to evaluate effects of a 2-year exposure to an electromagnetic near-field (EMF) equivalent to that generated by cellular phones on tumor development in the central nervous system (CNS) of rats. For this purpose, pregnant F344 rats were given a single administration of N-ethylnitrosourea (ENU) on gestational day 18. A total of 500 pups were divided into five groups, each composed of 50 males and 50 females: Group 1, untreated controls; Group 2, ENU alone; Groups 3 to 5, ENU + EMF (sham exposure and two exposure levels). A 1.95-GHz wide-band code division multiple access (W-CDMA) signal, which is a feature of the International Mobile Telecommunication 2000 (IMT-2000) cellular system was employed for exposure of the rat head starting from 5 weeks of age, 90 min a day, 5 days a week, for 104 weeks. Brain average specific absorption rates (SARs) were designed to be .67 and 2.0 W/kg for low and high exposures, respectively. The incidence and numbers of brain tumors in female rats exposed to 1.95-GHz W-CDMA signals showed tendencies to increase but without statistical significance. Overall, no significant increase in incidences or numbers, either in the males or females, was detected in the EMF-exposed groups. In addition, no clear changes in tumor types in the brain were evident. Thus, under the present experimental conditions, exposure of heads of rats to 1.95-GHz W-CDMA signals for IMT-2000 for a 2-year period was not demonstrated to accelerate or otherwise affect ENU-initiated brain tumorigenesis. Bioelectromagnetics 28:562–572, 2007. © 2007 Wiley-Liss, Inc.read more
Citations
More filters
Journal ArticleDOI
The controversy about a possible relationship between mobile phone use and cancer.
TL;DR: The overall evidence speaks in favor of an increased risk of brain tumors, but its magnitude cannot be assessed at present because of insufficient information on long-term use.
Journal ArticleDOI
Systematic review of wireless phone use and brain cancer and other head tumors
Michael Repacholi,Alexander Lerchl,Martin Röösli,Zenon Sienkiewicz,Anssi Auvinen,Jürgen Breckenkamp,Guglielmo d'Inzeo,Paul Elliott,Patrizia Frei,Sabine Heinrich,Isabelle Lagroye,Anna Lahkola,David L. McCormick,Silke Thomas,Paolo Vecchia +14 more
TL;DR: Assessment of the review results using the Hill criteria did not support a causal relationship between wireless phone use and the incidence of adult cancers in the areas of the head that most absorb RF energy from the use of wireless phones.
Book
Advances in Electromagnetic Fields in Living Systems
TL;DR: In this article, the charge-to-mass ICR Signature in Weak ELF Bioelectromagnetic Effects was used to detect weak ELF bioelectromagnetism effects.
Journal ArticleDOI
Recent advances in research on radiofrequency fields and health: 2001-2003.
Daniel Krewski,Barry W. Glickman,Riadh W. Y. Habash,Brian Habbick,W Gregory Lotz,Rosemonde Mandeville,Frank S. Prato,Tarek Salem,Donald F. Weaver +8 more
TL;DR: New data on dosimetry and exposure assessment, biological effects such as enzyme induction, and toxicological effects, including genotoxicity, carcinogenicity, and testicular and reproductive outcomes are examined, along with human and animal studies of neurological and behavioral effects.
Journal ArticleDOI
Lack of Adverse Effects of Whole-Body Exposure to a Mobile Telecommunication Electromagnetic Field on the Rat Fetus
Satoru Takahashi,Norio Imai,Kyoko Nabae,Kanako Wake,Hiroki Kawai,Jianqing Wang,Soichi Watanabe,Mayumi Kawabe,Osamu Fujiwara,Kumiko Ogawa,Seiko Tamano,Tomoyuki Shirai +11 more
TL;DR: Under experimental conditions, whole-body exposure to 2.14 GHz for 20 h per day during gestation and lactation did not cause any adverse effects on pregnancy or the development of rats.
References
More filters
Journal Article
Guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields (up to 300 GHz)
TL;DR: The International Commission on Non-Ionizing Radiation Protection (ICNIRP)—was established as a successor to the IRPA/INIRC, which developed a number of health criteria documents on NIR as part of WHO’s Environmental Health Criteria Programme, sponsored by the United Nations Environment Programme (UNEP).
Journal ArticleDOI
Comments concerning "Guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields (up to 300 GHz)".
Journal ArticleDOI
Cellular-Telephone Use and Brain Tumors
Peter D. Inskip,Robert E. Tarone,Elizabeth E. Hatch,Timothy C. Wilcosky,William R. Shapiro,Robert G. Selker,Howard A. Fine,Peter McL. Black,Jay S. Loeffler,Martha S. Linet +9 more
TL;DR: Data do not support the hypothesis that the recent use of hand-held cellular telephones causes brain tumors, but they are not sufficient to evaluate the risks among long-term, heavy users and for potentially long induction periods.
Journal ArticleDOI
Handheld Cellular Telephone Use and Risk of Brain Cancer
Joshua E. Muscat,Mark G. Malkin,Seth Thompson,Roy E. Shore,Steven D. Stellman,Don McRee,Alfred I. Neugut,Ernst L. Wynder +7 more
TL;DR: The data suggest that use of handheld cellular telephones is not associated with risk of brain cancer, but further studies are needed to account for longer induction periods, especially for slow-growing tumors with neuronal features.
Journal ArticleDOI
Cellular Telephones and Cancer—a Nationwide Cohort Study in Denmark
TL;DR: In this paper, the first nationwide cancer incidence study of cellular phone users, do not support the hypothesis of an association between use of these telephones and tumors of the brain or salivary gland, leukemia, or other cancers.