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Journal ArticleDOI

LEGIONELLACEAE IN THE HOSPITAL WATER-SUPPLY: Epidemiological Link with Disease and Evaluation of a Method for Control of Nosocomial Legionnaires' Disease and Pittsburgh Pneumonia

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TLDR
An epidemiological link was found between contamination of a hospital water-supply by Legionella pneumophila and by Pittsburgh pneumonia agent (PPA) and subsequent cases of nosocomial legionnaires' disease and Pittsburgh pneumonia.
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This article is published in The Lancet.The article was published on 1983-08-06. It has received 242 citations till now. The article focuses on the topics: Hospital-acquired pneumonia & Legionnaires' disease.

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Citations
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Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC)

TL;DR: This report reviews previous guidelines and strategies for preventing environment-associated infections in health-care facilities and offers recommendations, including evidence-based recommendations supported by studies and experienced opinions based upon infection-control and engineering practices.
Journal Article

Guidelines for Preventing Health-Care-- Associated Pneumonia, 2003 Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee

TL;DR: The new guidelines are designed to reduce the incidence of pneumonia and other severe, acute lower respiratory tract infections in acute-care hospitals and in other health-care settings (e.g., ambulatory and longterm care institutions) and other facilities where health care is provided.
Journal Article

Guidelines for environmental infection control in health-care facilities. Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC).

TL;DR: A review of previous guidelines and strategies for preventing environment-associated infections in health-care facilities and offers recommendations can be found in this article, where the authors suggest a series of performance measurements as a means to evaluate infection-control efforts.

Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee

TL;DR: The new guidelines are designed to reduce the incidence of pneumonia and other severe, acute lower respiratory tract infections in acute-care hospitals and in other health-care settings (e.g., ambulatory and long-term care institutions) and other facilities where health care is provided.
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Influence of temperature and plumbing material selection on biofilm formation and growth of Legionella pneumophila in a model potable water system containing complex microbial flora.

TL;DR: This work suggests that the use of copper tubing in water systems may help to limit the colonization of water systems by L. pneumophila.
References
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Journal Article

Causation and Disease: The Henle-Koch Postulates Revisited

TL;DR: The Henle-Koch postulates are reviewed in terms of their full validity in Koch's day and in light of subsequent developments, and a set of guidelines for both acute infectious and chronic diseases is presented.
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Legionnaires' disease: report of sixty-five nosocomially acquired cases of review of the literature.

TL;DR: The diagnosis of Legionnaires' disease during acute illness may be established by culture of Legionella pneumophila, or by demonstration of the bacterium using special stains, but in most instances the physician must make a presumptive diagnosis based on the clinical presentation in order to institute appropriate antimicrobial therapy.
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Detection of Legionnaires disease bacteria by direct immunofluorescent staining.

TL;DR: The conjugates prepared for five strains of the Legionnaires bacteria were successfully used to detect Legionnaires disease bacteria in Formalin-fixed lung scrapings, in histological sections, and in fresh lung tissue obtained at biopsy or autopsy.
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Hot water systems as sources of Legionella pneumophila in hospital and nonhospital plumbing fixtures.

TL;DR: It is hypothesized that hot-water tanks are a breeding site and a major source of L. pneumophila for the contamination of plumbing systems and tanks and the extent of the hazard of this contamination needs to be delineated.
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