Journal ArticleDOI
LOPH: a novel chemotherapeutic protocol for feline high-grade multicentric or mediastinal lymphoma, developed in an area endemic for feline leukemia virus.
Rodrigo dos Santos Horta,Larissa M Souza,Bruna Voltolin de Sena,Isabella Oliveira Almeida,Tâmara de Almeida Jaretta,Marcela Malvini Pimenta,Archivaldo Reche Junior +6 more
TLDR
The LOPH protocol was well tolerated by cats with lymphoma and persistent FeLV viremia, and resulted in a better MST than similar studies with other protocols.Abstract:
ObjectivesThe aim of this study was to establish the safety and efficacy of a novel multidrug lomustine-based chemotherapeutic protocol for cats with high-grade multicentric or mediastinal lymphoma...read more
Citations
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Journal ArticleDOI
Effects of Chemotherapy on Hematological Parameters and CD4+/CD8+ Ratio in Cats with Mediastinal Lymphoma and Seropositive to Feline Leukemia Virus
TL;DR: The results suggested that COP chemotherapy is safe as a treatment for FeLV-infected cats with mediastinal lymphoma, and evaluated the effect of the COP chemotherapeutic protocol on hematological parameters, CD4+/CD8+ ratio, and the mortality of 18 client-owned Fe LV- infected cats.
Prevalência de Leucemia Felina em Gatos Domésticos de Uberlândia - MG
Fernando Cristino Barbosa,Maria Paula de Tullio Christianine,Katia Cristina Andrade Waldemarin +2 more
TL;DR: In this article, a study of 70 gatos atendidos no Hospital Veterinario da Universidade Federal de Uberlândia and 55 amostras do Centro de Zoonoses de Uberlan et al. showed that 60% dos gatos expostos ao virus desenvolvem uma resposta imune logo apos uma exposicao inicial.
Journal ArticleDOI
Lomustine, methotrexate and cytarabine chemotherapy as a rescue treatment for feline lymphoma.
TL;DR: This study suggests that lomustine, methotrexate and cytarabine may represent an efficacious and well-tolerated protocol for feline lymphoma rescue.
Journal ArticleDOI
Effectiveness and Adverse Events of Cyclophosphamide, Vincristine, and Prednisolone Chemotherapy in Feline Mediastinal Lymphoma Naturally Infected with Feline Leukemia Virus
Supita Sunpongsri,Attawit Kovitvadhi,Jatuporn Rattanasrisomporn,Viphavee Trisaksri,Nichakorn Jensirisak,Tassanee Jaroensong +5 more
TL;DR: The overall response rate and median survival time of cats with feline lymphoma that were FeLV-antigen-positive and treated with COP chemotherapy were higher than from other studies, and cats aged <4 years survived longer than those aged at least 4 years.
Journal ArticleDOI
LOPH and D-MHC in the Treatment of FeLV Associated Acute Leukemia in a Cat
Rodrigo dos Santos Horta,Ana Luísa Fajardo Ferreira,Mariana de Pádua Costa,Ligia Soares Frossard,Júlia Campero Nimrichter,Mylena Duarte de Carli,Paulo Ricardo de Oliveira Paes +6 more
TL;DR: A case of a cat presenting with FeLV associated acute leukemia and treated with the LOPH protocol, and, in the rescue phase, a modification of the D-MAC protocol, denominated D-MHC, resulted in a longer survival time than reported in other studies.
References
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Journal ArticleDOI
Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in North America and risk factors for seropositivity
TL;DR: Results suggest that certain characteristics, such as age, sex, health status, and lifestyle, are associated with risk of FeLV and FIV seropositivity among cats in North America, and current guidelines to test all cats at the time of acquisition and again during illness should be followed.
Journal ArticleDOI
Feline lymphoma in the post-feline leukemia virus era
TL;DR: A significant decrease in the importance of FeLV-associated types of lymphoma in cats is confirmed and Associations of intestinal lymphoma and inflammatory bowel disease and diet should be further considered.
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Feline Lymphoma (145 Cases): Proliferation Indices, Cluster of Differentiation 3 Immunoreactivity, and Their Association with Prognosis in 90 Cats
TL;DR: Paraffin-embedded, formalin-fixed tissue samples from 145 cats with lymphoma were analyzed for cluster of differentiation 3 (CD3, a surface antigen) immunoreactivity, argyrophilic nucleolar organizer region (AgNOR) frequency, and proliferating cell nuclear antigen labeling index (PCNA-LI) to determine the potential of these indicators to predict response to therapy, remission, and survival times.
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Histopathologic classification of 171 cases of canine and feline non‐Hodgkin lymphoma according to the WHO
TL;DR: A retrospective collection of 171 lymphoid neoplasms was classified according to the Revised European-American Lymphoma (REAL) classification, adopted in 2002 by the World Health Organization, to evaluate the WHO system for categorization of canine and feline neoplasm.
Journal Article
Feline immunodeficiency virus and feline leukemia virus infections and their relationships to lymphoid malignancies in cats: a retrospective study (1968-1988).
TL;DR: A significant correlation between FIV infection and lymphoproliferative malignancies was also found independent of FeLV infection, and a strong correlation between FeLV viremia and leukemia/lymphoma was confirmed.