Lymph node dissection at the time of radical nephrectomy for high-risk clear cell renal cell carcinoma: indications and recommendations for surgical templates
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The pathologist must be aware of this condition and look for vasculitis whenever a patient with an infarcted testis has no history of torsion or trauma and all patients should be clinically investigated for systemic disease.Abstract:
Editorial Comment This is a large series of a rare condition in the testis. Testicular vasculitis can cause localized infarction that clinically may mimic cancer (1). Testicular vasculitis may be an isolated finding, however, in most patients is associated with systemic vasculitis. All patients should be clinically investigated for systemic disease. In this series of 19 cases the mean age was 38 years and most cases (n = 14) showed polyarteritis nodosa-like features with transmural necrotizing inflammation of small-medium arteries (2). The pathologist must be aware of this condition and look for vasculitis whenever a patient with an infarcted testis has no history of torsion or trauma.read more
Citations
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Journal ArticleDOI
Lymph Node Dissection in Renal Cell Carcinoma
Umberto Capitanio,F. Becker,Michael L. Blute,Peter F.A. Mulders,Jean-Jacques Patard,Paul Russo,Urs E. Studer,Hendrik Van Poppel +7 more
TL;DR: To date, the available evidence suggests that an extended LND may be beneficial when technically feasible in patients with locally advanced disease and/or unfavorable clinical and pathologic characteristics, and the majority of retrospective nonrandomized trials seem to suggest a possible benefit of regional LND even for this group of patients.
Journal ArticleDOI
Systematic review of adrenalectomy and lymph node dissection in locally advanced renal cell carcinoma.
Hendrika J. Bekema,Steven MacLennan,Mari Imamura,Thomas B. Lam,Thomas B. Lam,Fiona Stewart,Neil W. Scott,Graeme MacLennan,Samuel McClinton,T.R. Leyshon Griffiths,Andreas Skolarikos,Sara MacLennan,Richard Sylvester,Börje Ljungberg,James N'Dow,James N'Dow +15 more
TL;DR: There is insufficient evidence to draw any conclusions on oncologic outcomes for patients having concomitant LND or ipsilateral adrenalectomy compared with patients having RN alone for cT3-T4N0M0 RCC.
Journal ArticleDOI
Can a durable disease-free survival be achieved with surgical resection in patients with pathological node positive renal cell carcinoma?
Scott E. Delacroix,Brian F. Chapin,Jaclyn Jin-Ling Chen,Graciela M. Nogueras-Gonzalez,Pheroze Tamboli,Surena F. Matin,Christopher G. Wood +6 more
TL;DR: Nephrectomy with lymph node dissection can provide a durable disease-free survival in a proportion of patients with regionally advanced renal cell carcinoma and limited lymph node metastases.
Journal ArticleDOI
Retroperitoneal Lymphadenectomy for High Risk, Nonmetastatic Renal Cell Carcinoma: An Analysis of the ASSURE (ECOG-ACRIN 2805) Adjuvant Trial
Benjamin T. Ristau,Judi Manola,Naomi B. Haas,Daniel Y.C. Heng,Edward M. Messing,Christopher G. Wood,Christopher J. Kane,Robert S. DiPaola,Robert G. Uzzo +8 more
TL;DR: The benefit of lymphadenectomy in patients undergoing surgery for high risk renal cell carcinoma remains uncertain and future strategies to answer this question should include a prospective trial in which patients with high risk Renal Carcinoma are randomized to specificymphadenectomy templates.
Journal ArticleDOI
Imaging in the follow-up of renal cell carcinoma.
Uday Patel,Heminder Sokhi +1 more
TL;DR: The normal posttreatment findings and the distribution and the signs of relapsed disease are described and imaging follow-up protocols should be tailored according to the clinical scenario.
References
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Journal ArticleDOI
Lymph Node Dissection in Renal Cell Carcinoma
Umberto Capitanio,F. Becker,Michael L. Blute,Peter F.A. Mulders,Jean-Jacques Patard,Paul Russo,Urs E. Studer,Hendrik Van Poppel +7 more
TL;DR: To date, the available evidence suggests that an extended LND may be beneficial when technically feasible in patients with locally advanced disease and/or unfavorable clinical and pathologic characteristics, and the majority of retrospective nonrandomized trials seem to suggest a possible benefit of regional LND even for this group of patients.
Journal ArticleDOI
Systematic review of adrenalectomy and lymph node dissection in locally advanced renal cell carcinoma.
Hendrika J. Bekema,Steven MacLennan,Mari Imamura,Thomas B. Lam,Thomas B. Lam,Fiona Stewart,Neil W. Scott,Graeme MacLennan,Samuel McClinton,T.R. Leyshon Griffiths,Andreas Skolarikos,Sara MacLennan,Richard Sylvester,Börje Ljungberg,James N'Dow,James N'Dow +15 more
TL;DR: There is insufficient evidence to draw any conclusions on oncologic outcomes for patients having concomitant LND or ipsilateral adrenalectomy compared with patients having RN alone for cT3-T4N0M0 RCC.
Journal ArticleDOI
Can a durable disease-free survival be achieved with surgical resection in patients with pathological node positive renal cell carcinoma?
Scott E. Delacroix,Brian F. Chapin,Jaclyn Jin-Ling Chen,Graciela M. Nogueras-Gonzalez,Pheroze Tamboli,Surena F. Matin,Christopher G. Wood +6 more
TL;DR: Nephrectomy with lymph node dissection can provide a durable disease-free survival in a proportion of patients with regionally advanced renal cell carcinoma and limited lymph node metastases.
Journal ArticleDOI
Retroperitoneal Lymphadenectomy for High Risk, Nonmetastatic Renal Cell Carcinoma: An Analysis of the ASSURE (ECOG-ACRIN 2805) Adjuvant Trial
Benjamin T. Ristau,Judi Manola,Naomi B. Haas,Daniel Y.C. Heng,Edward M. Messing,Christopher G. Wood,Christopher J. Kane,Robert S. DiPaola,Robert G. Uzzo +8 more
TL;DR: The benefit of lymphadenectomy in patients undergoing surgery for high risk renal cell carcinoma remains uncertain and future strategies to answer this question should include a prospective trial in which patients with high risk Renal Carcinoma are randomized to specificymphadenectomy templates.
Journal ArticleDOI
Imaging in the follow-up of renal cell carcinoma.
Uday Patel,Heminder Sokhi +1 more
TL;DR: The normal posttreatment findings and the distribution and the signs of relapsed disease are described and imaging follow-up protocols should be tailored according to the clinical scenario.