Showing papers in "European Urology in 2011"

TL;DR: A summary of the 2010 version of the EAU guidelines on the treatment of advanced, relapsing, and castration-resistant prostate cancer (CRPC) summarise the most recent findings and put them into clinical practice.

TL;DR: Current evidence is insufficient to warrant widespread population-based screening by prostate-specific antigen (PSA) for PCa, and these EAU guidelines on PCa summarise the most recent findings and put them into clinical practice.

TL;DR: Large collaborative studies with uniform data collection seem to be necessary to elucidate a complete list of established risk factors of RCC to make successful prevention possible for a disease that is diagnosed frequently in a stage where curative treatment is not possible anymore.

TL;DR: Consensus was reached on a number of areas related to the conduct, interpretation, and reporting of mpMRI for the detection, localisation, and characterisation of prostate cancer.

TL;DR: Current data demonstrate that neoadjuvant chemotherapy in conjunction with radical cystectomy (RC) is recommended in certain constellations of MiM-BC, and a new drug for second-line chemotherapy (vinflunine) in metastatic disease has been approved and is recommended.

TL;DR: These abridged EAU guidelines present updated information on the diagnosis and treatment of NMIBC for incorporation into clinical practice and the stratification of patients into low, intermediate, and high-risk groups is pivotal to recommending adjuvant treatment.

TL;DR: MiRNAs appear to be important modulators of urologic cancer, and many are functionally implicated in their pathogenesis.

TL;DR: This is the first SRM active surveillance study to correlate growth with histology prospectively, and shows that SRMs appear to grow very slowly, even if biopsy proven to be RCC.

TL;DR: OnabotulinumtoxinA significantly reduced UI and improved urodynamics and QOL in MS and SCI patients with NDO in a multicentre, randomised, double-blind, placebo-controlled study.

TL;DR: Evidence in the peer-reviewed literature suggested that chronic prostatic inflammation may be involved in the development and progression of Chronic prostatic disease, such as BPH and PCa, although there is still no evidence of a causal relation.

TL;DR: Although there is no conclusive evidence that a varicocele repair improves spontaneous pregnancy rates, varicocelectomy improves sperm parameters (count and total and progressive motility), reduces sperm DNA damage and seminal oxidative stress, and improves sperm ultramorphology.

TL;DR: RTB can be performed safely and accurately in the investigation of renal masses ≤ 4 cm and a nondiagnostic biopsy should be considered a surrogate for the absence of malignancy, providing a diagnosis for most patients.

TL;DR: A summary of the 2009 update of the EAU guidelines on urinary incontinence, which provides ratings of the evidence and graded recommendations for the appropriate assessment and according treatment options and put them into clinical perspective is presented.

TL;DR: These guidelines contain information for the standardised management of patients with testicular cancer based on the latest scientific insights, and treatment must be tailored taking individual circumstances and patient preferences into account.

TL;DR: This analysis provides, for the first time, anchor-based estimates of MCIDs in the EF domain score of the IIEF, and shows how the contextualization of treatment-related changes in terms of clinically relevant improvement is essential to understanding treatment efficacy, to interpreting results across studies, and to managing patients effectively.

TL;DR: New guidelines for urothelial cell carcinoma of the upper urinary tract have been prepared to aid clinicians in assessing the current evidence-based management of UUT-UCC and to incorporate present recommendations into daily clinical practice.

TL;DR: A novel technique of "zero ischemia" laparoscopic and robotic-assisted partial nephrectomy and LPN for substantial renal tumors is presented and the initial experience is encouraging.

TL;DR: Initial data indicate that multimodal ICG-(99m)Tc-NanoColloid, in combination with a laparoscopic fluorescence laparoscope, can be used to facilitate and optimize dissection of SLNs during RALP procedures.

TL;DR: Several prognostic factors can help discriminate between favourable and unfavourable RCC phenotypes, and several clinical, pathologic, and biologic markers have been tested and validated and they are used in predictive and prognostic models.

TL;DR: There is an ongoing need for identifying novel and more accurate predictors of Ins-PCa to improve the distinction between insignificant versus significant disease and thus to promote the adequate management of PCa patients at low risk for progression.

TL;DR: Compared with TURP, 120-W GLL PVP is safe and effective in treatment of BPH and shows dramatic improvement in Q(max), IPSS, and PVP compared with preoperative values and the degree of improvement was comparable in both groups at all time points of follow-up.

TL;DR: The incidence rates of localized RCC increased rapidly, whereas those of distant RCC declined, and Mortality rates significantly increased for localized stage and decreased for distant stage.

TL;DR: This narrative review describes recent progress in exosome research, focusing on the potential role of exosomes as novel biomarkers for prostate cancer (PCa), to acquaint clinicians and researchers in the field of urology with the potential roles of exOSomes as biomarker treasure chests and with their clinical value.

TL;DR: Only a minority of men experience systemic progression and death from PCa following RRP, and the decision to institute secondary therapies must balance the risk of disease progression with the cost and morbidity of treatment, independent of time from RRP to BCR.

TL;DR: It is believed that pentafecta outcomes more accurately represent patients' expectations after minimally invasive surgery for prostate cancer.

TL;DR: This study provides a global view of the evolution of LESS in the field of minimally invasive urologic surgery and shows that a broad range of procedures have been effectively performed, primarily in the academic setting, within diverse health care systems around the world.

TL;DR: A single postoperative dose of intravesical MMC appears to reduce the risk of a bladder tumour within the first year following nephroureterectomy for UUTUC, with an absolute reduction in risk of 11%, the relative reduction inrisk is 40%, and the number needed to treat to prevent one bladder tumours is nine.

TL;DR: A consensus is presented with respect to the physics and techniques used by urologists, physicists, and representatives of European lithotripter companies on optimising shock wave application to significantly increase the efficacy and safety of ESWL.