Journal ArticleDOI
Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer
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TLDR
Meta-analysis of cohort or case-control studies with age- and/or sex-matched controls with raw data on H. pylori infection found the source of heterogeneity between studies was caused by differences in the selection of controls, patient age, and the site and stage of gastric cancer.About:
This article is published in Gastroenterology.The article was published on 1998-06-01. It has received 904 citations till now. The article focuses on the topics: Helicobacter pylori & Cancer.read more
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Helicobacter pylori infection and the development of gastric cancer
Naomi Uemura,Sumika Okamoto,Susumu Yamamoto,Nobuyuki Matsumura,Shigeki Yamaguchi,Michio Yamakido,Kiyomi Taniyama,Noboyuki Sasaki,Ronald J Schlemper +8 more
TL;DR: Gastric cancer develops in persons infected with H. pylori but not in uninfected persons, and those with histologic findings of severe gastric atrophy, corpus-predominant gastritis, or intestinal metaplasia are at increased risk.
Journal ArticleDOI
The global health burden of infection-associated cancers in the year 2002.
TL;DR: The fraction of the different types of cancer, and of all cancers worldwide and in different regions, has been estimated using several methods; primarily by reviewing the evidence for the strength of the association (relative risk) and the prevalence of infection in different world areas.
Journal ArticleDOI
Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis
James K.Y. Hooi,Wan Ying Lai,Wee Khoon Ng,Wee Khoon Ng,Michael M.Y. Suen,Fox E. Underwood,Divine Tanyingoh,Peter Malfertheiner,David Y. Graham,Vincent Wai-Sun Wong,Justin C.Y. Wu,Francis K.L. Chan,Joseph J.Y. Sung,Gilaad G. Kaplan,Siew C. Ng +14 more
TL;DR: Large amounts of variation among regions are observed among regions-more than half the world's population is infected, which can be used in development of customized strategies for the global eradication.
Journal ArticleDOI
Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial.
Benjamin C.Y. Wong,Shiu Kum Lam,Wai Man Wong,Jian Shun Chen,Ting Ting Zheng,Rui E. Feng,Kam Chuen Lai,Wayne Hsing Cheng Hu,Siu Tsan Yuen,Suet Yi Leung,Daniel Y. T. Fong,Joanna Ho,Chi Kong Ching,Jun Shi Chen +13 more
TL;DR: It was found that the incidence of gastric cancer development at the population level was similar between participants receiving H pylori eradication treatment and those receiving placebo during a period of 7.5 years in a high-risk region of China.
Journal ArticleDOI
Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial.
Kazutoshi Fukase,Mototsugu Kato,Shogo Kikuchi,Kazuhiko Inoue,Naomi Uemura,Shiro Okamoto,Shuichi Terao,Kenji Amagai,Shunji Hayashi,Masahiro Asaka +9 more
TL;DR: Prophylactic eradication of H pylori after endoscopic resection of early gastric cancer should be used to prevent the development of metachronous gastric carcinoma.
References
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Meta-Analysis in Clinical Trials*
TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.
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Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease
Nathan Mantel,William Haenszel +1 more
TL;DR: In this paper, the role and limitations of retrospective investigations of factors possibly associated with the occurrence of a disease are discussed and their relationship to forward-type studies emphasized, and examples of situations in which misleading associations could arise through the use of inappropriate control groups are presented.
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The two histological main types of gastric carcinoma; diffuse and so-called intestinal-type carcinoma. an attempt at a histo-clinical classification
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Helicobacter pylori infection and the risk of gastric carcinoma.
Julie Parsonnet,Gary D. Friedman,Daniel P. Vandersteen,Yuan Chang,Joseph H. Vogelman,Norman Orentreich,Richard K. Sibley +6 more
TL;DR: Infection with H. pylori is associated with an increased risk of gastric adenocarcinoma and may be a cofactor in the pathogenesis of this malignant condition.
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Unidentified curved bacilli on gastric epithelium in active chronic gastritis
J R Warren,Barry J. Marshall +1 more
TL;DR: Gastric biopsy findings are classified according to the type of inflammation, regardless of other features, as "no inflammation", "chronic gastritis", or "active chronic gastritis" (ACG).