Journal ArticleDOI
Metabolism and toxicity of aluminum in renal failure.
TLDR
It is suggested that dialysis encephalopathy occurs as a result of such rapid aluminum loading during dialysis that bone's ability to sequester this element is overcome, and it is shunted to liver and brain with resulting toxicity.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 1980-07-01. It has received 259 citations till now. The article focuses on the topics: Dialysis Encephalopathy & Uremia.read more
Citations
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Journal ArticleDOI
Bone metabolism and disease in chronic kidney disease
Journal ArticleDOI
Human Health Risk Assessment for Aluminium, Aluminium Oxide, and Aluminium Hydroxide
Daniel Krewski,Robert A. Yokel,Evert Nieboer,David R. Borchelt,Joshua T. Cohen,Jean Harry,Sam Kacew,Joan Lindsay,Amal M Mahfouz,Virginie Rondeau +9 more
TL;DR: This article was originally published with an incorrect version of the Acknowledgments, which appeared on p. 218 of the print version.
Journal ArticleDOI
Metabolism and possible health effects of aluminum.
TL;DR: A hypothetical model is presented for the metabolism of aluminum, based on documented direct observations of Al3+ and analogies from other ions, and it is proposed that an accumulation may take place at a subcellular level without any significant increase in the corresponding tissue concentration.
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Aluminum Intoxication from Aluminum-Containing Phosphate Binders in Children with Azotemia Not Undergoing Dialysis
TL;DR: It is indicated that gastrointestinal absorption of aluminum can lead to aluminum intoxication in children with azotemia, and that infants may be particularly susceptible to this complication of therapy.
References
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Journal ArticleDOI
Brain aluminum distribution in Alzheimer's disease and experimental neurofibrillary degeneration.
TL;DR: In this article, aluminum concentrations approaching those used experimentally have been found in some regions of the brains of patients with Alzheimer's disease, which is an important pathological finding in senile and presenile dementia of the Alzheimer type.
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Trace elements in human tissue. part ii. adult subjects from the united states
Isabel H. Tipton,M. J. Cook +1 more
TL;DR: In this article, central values and an estimate of the variation about the central values are given for 24 trace elements and the dry, and ash content of samples of 29 different tissues of 150 adult victims of instantaneous death who had spent their lives in the United States.
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Gastrointestinal absorption of aluminum from aluminum-containing antacids.
TL;DR: An extensive review of biologic aspects of aluminum found no evidence to support absorption of orally administered aluminum compounds, and no definitive studies of changes in plasma and urinary levels in normal persons who ingest aluminum have been reported.
Journal ArticleDOI
Aluminum absorption and distribution: effect of parathyroid hormone.
TL;DR: In rats, gastrointestinal aluminum absorption and tissue distribution were altered by parathyroid hormone; the resultant tissue concentrations were similar to those observed in Dialysis patients with a fatal encephalopathy, suggesting that aluminum toxicity in dialysis patients results from oral aluminum ingestion in the presence of hyperparathyroidism.
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Measuring picogram amounts of aluminum in biological tissue by flameless atomic absorption analysis of a chelate.
G R LeGendre,A C Alfrey +1 more
TL;DR: The extraction simplifies the method and virtually eliminates contamination with extraneous aluminum during the analysis, and the technique appears to be more sensitive than other methods of aluminum determination used for biological samples.