Open AccessBook
Methodology for Genetic Studies of Twins and Families
Michael C. Neale,Lon R. Cardon +1 more
TLDR
The LISREL Script for Rater Bias Model and Data for Simplex Model as mentioned in this paper is one of the most well-known models in the literature for gene expression analysis.Abstract:
Preface. List of Figures. List of Tables. 1. The Scope of Genetic Analyses. 2. Data Summary. 3. Biometrical Genetics. 4. Matrix Algebra. 5. Path Analysis and Structural Equations. 6. LISREL Models and Methods. 7. Model Fitting Functions and Optimization. 8. Univariate Analysis. 9. Power and Sample Size. 10. Social Interaction. 11. Sex Limitation and GE Interaction. 12. Multivariate Analysis. 13. Direction of Causation. 14. Repeated Measures. 15. Longitudinal Mean Trends. 16. Observer Ratings. 17. Assortment and Cultural Transmission. 18. Future Directions. Appendices: A. List of Participants. B. The Greek Alphabet. C. LISREL Scripts for Univariate Models. D. LISREL Script for Power Calculation. E. LISREL Scripts for Multivariate Models. F. LISREL Script for Sibling Interaction Model. G. LISREL Scripts for Sex and GE Interaction. H. LISREL Script for Rater Bias Model. I. LISREL Scripts for Direction of Causation. J. LISREL Script and Data for Simplex Model. K. LISREL Scripts for Assortment Models. Bibliography. Index.read more
Citations
More filters
Book ChapterDOI
Structural Equation Modeling
TL;DR: The theory of SEM, which allows for the analysis of independent observations for both unrelated and family data, the available software for SEM, and an example of SEM analysis are reviewed.
Journal ArticleDOI
Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland
Paul Lichtenstein,Niels V. Holm,Pia K. Verkasalo,Anastasia Iliadou,Jaakko Kaprio,Jaakko Kaprio,Markku Koskenvuo,Markku Koskenvuo,Eero Pukkala,Axel Skytthe,Kari Hemminki +10 more
TL;DR: Inherited genetic factors make a minor contribution to susceptibility to most types of neoplasms, which indicates that the environment has the principal role in causing sporadic cancer.
Journal ArticleDOI
Genetic dissection of complex traits
TL;DR: This article synthesizes the current state of the genetic dissection of complex traits--describing the methods, limitations, and recent applications to biological problems.
Journal ArticleDOI
An atlas of genetic correlations across human diseases and traits.
Brendan Bulik-Sullivan,Brendan Bulik-Sullivan,Hilary K. Finucane,Verneri Anttila,Verneri Anttila,Alexander Gusev,Felix R. Day,Po-Ru Loh,Po-Ru Loh,Laramie E. Duncan,Laramie E. Duncan,John R. B. Perry,Nick Patterson,Elise B. Robinson,Elise B. Robinson,Mark J. Daly,Mark J. Daly,Alkes L. Price,Alkes L. Price,Benjamin M. Neale,Benjamin M. Neale +20 more
TL;DR: This work introduces a technique—cross-trait LD Score regression—for estimating genetic correlation that requires only GWAS summary statistics and is not biased by sample overlap, and uses this method to estimate 276 genetic correlations among 24 traits.
Journal ArticleDOI
Genetic Epidemiology of Major Depression: Review and Meta-Analysis
TL;DR: A meta-analysis of relevant data from primary studies of the genetic epidemiology of major depression suggested that familial aggregation was due to additive genetic effects, with a minimal contribution of environmental effects common to siblings and substantial individual-specific environmental effects/measurement error.
References
More filters
Book
Introduction to quantitative genetics
TL;DR: The genetic constitution of a population: Hardy-Weinberg equilibrium and changes in gene frequency: migration mutation, changes of variance, and heritability are studied.
Book
Structural Equations with Latent Variables
TL;DR: The General Model, Part I: Latent Variable and Measurement Models Combined, Part II: Extensions, Part III: Extensions and Part IV: Confirmatory Factor Analysis as discussed by the authors.
Book
Modern factor analysis
TL;DR: The third edition of HARMAN's authoritative text as mentioned in this paper incorporates the many new advances made in computer science and technology over the last ten years The author gives full coverage to both theoretical and applied aspects of factor analysis from its foundations through the most advanced techniques This highly readable text will be welcomed by researchers and students working in psychology, statistics, economics and related disciplines
Journal ArticleDOI
Child/adolescent behavioral and emotional problems: implications of cross-informant correlations for situational specificity.
TL;DR: Etude de la coherence entre differentes sources (269 echantillons utilisees dans 119 etudes) concernant les evaluations des problemes affectifs et comportementaux d'enfants et d'adolescents âges de 1 1/2 a 19 ans.
Book
Manual for the Child: Behavior Checklist and Revised Child Behavior Profile
TL;DR: In this article, the Association of Science, Education, and Technology (SBSPro) published a survey on the state of the art in early childhood special education in South Korea.