Minimum clinically important difference for the COPD Assessment Test: a prospective analysis
Samantha S.C. Kon,Jane L. Canavan,Sarah E. Jones,Claire M. Nolan,Amy L. Clark,Mandy J. Dickson,Brigitte M. Haselden,Michael I. Polkey,William D.-C. Man +8 more
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TLDR
The most reliable estimate of the minimum important difference of the CAT is 2 points, which could be useful in the clinical interpretation of CAT data, particularly in response to intervention studies.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2014-03-01 and is currently open access. It has received 447 citations till now. The article focuses on the topics: Minimal clinically important difference & Pulmonary rehabilitation.read more
Citations
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Indacaterol–Glycopyrronium versus Salmeterol–Fluticasone for COPD
Jadwiga A. Wedzicha,Donald Banerji,Kenneth R. Chapman,Jørgen Vestbo,Nicolas Roche,R Timothy Ayers,Chau Thach,Robert Fogel,Francesco Patalano,Claus Vogelmeier +9 more
TL;DR: Indacaterol-glycopyrronium was more effective than salmeterol-fluticasone in preventing COPD exacerbations in patients with a history of exacerbation during the previous year and showed not only noninferiority but also superiority in reducing the annual rate of all COPd exacerbations.
Journal ArticleDOI
Sarcopenia in COPD: prevalence, clinical correlates and response to pulmonary rehabilitation
Sarah E. Jones,Matthew Maddocks,Samantha S.C. Kon,Jane L. Canavan,Claire M. Nolan,Amy L. Clark,Michael I. Polkey,William D.-C. Man +7 more
TL;DR: Sarcopenia affects 15% of patients with stable COPD and impairs function and health status and does not impact on response to PR, which can lead to a reversal of the syndrome in select patients.
Journal ArticleDOI
Bronchoscopic lung volume reduction with endobronchial valves for patients with heterogeneous emphysema and intact interlobar fissures (the BeLieVeR-HIFi study): a randomised controlled trial
Claire Davey,Zaid Zoumot,Simon Jordan,William McNulty,Dennis H. Carr,Matthew Hind,David M. Hansell,Michael B. Rubens,Winston Banya,Michael I. Polkey,Pallav L. Shah,Nicholas S Hopkinson +11 more
TL;DR: Unilateral lobar occlusion with endobronchial valves in patients with heterogeneous emphysema and intact interlobar fissures produces significant improvements in lung function.
Journal ArticleDOI
Physical frailty and pulmonary rehabilitation in COPD: a prospective cohort study
Matthew Maddocks,Samantha S.C. Kon,Jane L. Canavan,Sarah E. Jones,Claire M. Nolan,Alex Labey,Michael I. Polkey,William D.-C. Man +7 more
TL;DR: In this article, the authors determined the prevalence of frailty among patients with stable COPD and examined whether frailty affects completion and outcomes of pulmonary rehabilitation and concluded that patients who are frail respond favourably to rehabilitation and their frailty can be reversed in the short term.
Journal ArticleDOI
The COPD assessment test: a systematic review
TL;DR: It is concluded that the studies support the reliability and validity of the CAT and that the tool is responsive to interventions, although the MCID remains debatable.
References
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Journal ArticleDOI
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
Jørgen Vestbo,Suzanne S. Hurd,Alvar Agusti,Paul W. Jones,Claus Vogelmeier,Antonio Anzueto,Peter J. Barnes,Leonardo M. Fabbri,Fernando J. Martinez,Masaharu Nishimura,Robert A. Stockley,Don D. Sin,Roberto Rodriguez-Roisin +12 more
TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
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Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary.
TL;DR: List of participants (GOLD Scientific Committee): Nicholas Anthonisen, Winnipeg, Canada, William C. Bailey, Birmingham, US, Tim Clark, London, UK, Leonardo Fabbri, Modena, Italy, Yoshinosuke Fukuchi, Tokyo, Japan; Lawrence Grouse, Seattle, US; James C. Hogg, Vancouver, Canada; Dirkje S. Postma, Groningen, the Netherlands.
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Interpretation of changes in health-related quality of life the remarkable universality of half a standard deviation
TL;DR: In most circumstances, the threshold of discrimination for changes in health-related quality of life for chronic diseases appears to be approximately half a SD, which research in psychology has shown is approximately 1 part in 7.
Journal ArticleDOI
Development and first validation of the COPD Assessment Test
TL;DR: The aim of the present study was to develop a short validated patient-completed questionnaire, the COPD Assessment Test (CAT), assessing the impact of COPD on health status, which has good measurement properties, is sensitive to differences in state and should provide a valid, reliable and standardised measure of COPd health status with worldwide relevance.
Journal ArticleDOI
Determining a minimal important change in a disease-specific quality of life questionnaire
TL;DR: The observation that the minimal important difference is consistent across domains and for both improvement and deterioration will facilitate interpretation of results of studies examining quality of life.
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