Journal ArticleDOI
Multifocal damage of the testis induced in rats by passive transfer of antibodies prepared against non-collagenous fraction of basement membrane
TLDR
Multifocal damage of the testis was induced in 70% of the rats injected with an antiserum against a non-collagenous fraction (D-STBM) obtained from a preparation enriched in basement membranes of seminiferous tubules.About:
This article is published in Journal of Reproductive Immunology.The article was published on 1985-01-01. It has received 22 citations till now. The article focuses on the topics: Seminiferous tubule & Basement membrane.read more
Citations
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Journal ArticleDOI
The Interplay of Collagen IV, Tumor Necrosis Factor-α, Gelatinase B (Matrix Metalloprotease-9), and Tissue Inhibitor of Metalloproteases-1 in the Basal Lamina Regulates Sertoli Cell-Tight Junction Dynamics in the Rat Testis
TL;DR: Results suggest that the activated MMP-9 induced by TNFalpha is used to cleave the existing collagen network in the ECM, thereby perturbing the TJ-barrier and strengthening the notion that ECM is involved in the regulation of junction dynamics in addition to its structural role in the testis.
Journal ArticleDOI
Ectoplasmic specialization: a friend or a foe of spermatogenesis?
TL;DR: The mechanisms that maintain the cross‐talk between ES and blood–testis barrier are discussed to facilitate cell movement and orientation in the seminiferous epithelium.
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An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective
C. Yan Cheng,Dolores D. Mruk +1 more
TL;DR: A novel apical ES-BTB-hemidesmosome regulatory loop is operating in the seminiferous epithelium to coordinate these two crucial cellular events of spermatogenesis, and a critical review based on the latest findings in the field regarding the regulation of these cellular events is provided.
Journal ArticleDOI
Extracellular Matrix: Recent Advances on Its Role in Junction Dynamics in the Seminiferous Epithelium During Spermatogenesis
Michelle K.Y. Siu,C. Yan Cheng +1 more
TL;DR: A timely update on this exciting yet rapidly developing field regarding how the homeostasis of basement membrane in the tunica propria regulates BTB dynamics and spermatogenesis in the testis is provided, as well as a critical review on the molecular architecture and the regulation of ES in the seminiferous epithelium.
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Sequential study of the histopathology and cellular and humoral immune response during the development of an autoimmune orchitis in Wistar rats.
TL;DR: A sequence of immunological events, concomitant with pathological changes of the testis, during the development of a severe EAO in Wistar rats is described.
References
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Journal ArticleDOI
Laminin--a glycoprotein from basement membranes.
Rupert Timpl,H Rohde,Pamela Gehron Robey,Stephen I. Rennard,Jean-Michel Foidart,George R. Martin +5 more
TL;DR: Investigation of a large noncollagenous glycoprotein isolated from a mouse tumor that produces basement membrane shows that it is produced by a variety of cultured cells, suggesting that this protein or an immunologically related protein is a constituent of the basement membranes of these tissues.
Journal Article
Application of a microtechnique to viral serological investigations.
TL;DR: A microtechnique (modified Takatsy) is described which can be applied to complement fixation, hemagglutination, hemagenesis inhibition and metabolic inhibition tests andComparative data obtained with the micro- and standard systems establish the reliability and validity of the microsystem.
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The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis.
TL;DR: It appears that patients forming anti-GBM antibodies may not be good candidates for renal transplantation since they are likely to produce in the transplants the nephritic changes already suffered by their own kidneys.
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Enzyme-linked immunoassay (ELISA) for connective tissue components
TL;DR: Enzyme-linked immunoadsorbant assays have been developed for types I, II, III, and IV collagen and for laminin and fibronectin and offer a specific, sensitive, and convenient method for the measurement of various connective tissue components either separately or simultaneously.