Journal ArticleDOI
NA gene frequencies in the German population, determined by polymerase chain reaction with sequence-specific primers.
TLDR
The NA2 gene is more frequent in the German population than the NA1 gene, as determined by genotyping using PCR‐SSP, in contrast to GIFT, which showed an error rate for NA typing of 15 percent.About:
This article is published in Transfusion.The article was published on 1995-01-01. It has received 132 citations till now. The article focuses on the topics: Typing & Genotyping.read more
Citations
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Journal ArticleDOI
Ten years of hemovigilance reports of transfusion-related acute lung injury in the United Kingdom and the impact of preferential use of male donor plasma
Catherine E. Chapman,Dorothy Stainsby,Hilary Jones,Elizabeth M. Love,Edwin Massey,Nay Win,Cristina Navarrete,Geoff Lucas,Neil Soni,Cliff Morgan,Louise Choo,Hannah Cohen,Lorna M. Williamson +12 more
TL;DR: A large number of cases were reported as transfusion‐related acute lung injury (TRALI) to the Serious Hazards of Transfusion scheme and from 1999 onward classified by probability, using clinical features and HLA and/or HNA typing.
Journal ArticleDOI
Neutrophil Fc gamma RIIIb deficiency, nature, and clinical consequences: a study of 21 individuals from 14 families.
TL;DR: Genotyping showed a normal Fc gamma RIIa phenotype distribution among the F c gamma RIIIb-negative individuals, thus excluding the possibility that the presence of the favorable IgG2-binding low-responder isoform of Fc Gamma RIIA (131-H) contributed to the overall absence of recurrent bacterial infections.
Journal ArticleDOI
Characterization of a New Alloantigen (SH) on the Human Neutrophil Fcγreceptor IIIb
Juergen Bux,Ernst-Ludwig Stein,Ernst-Ludwig Stein,Philippe Bierling,Philippe Bierling,Patricia Fromont,Patricia Fromont,Mary E. Clay,Mary E. Clay,David F. Stroncek,David F. Stroncek,Sentot Santoso,Sentot Santoso +12 more
TL;DR: The findings show the existence of an additional polymorphism of the FcγRIIIb, which can result in alloantibody formation causing alloimmune neonatal neutropenia.
Journal ArticleDOI
Human neutrophil alloantigens
TL;DR: Alloantigens currently listed in the human neutrophil alloantigen (HNA) system are described and described in detail.
Journal ArticleDOI
Report on the second international granulocyte serology workshop
Juergen Bux,J Chapman +1 more
TL;DR: A combination of the GIFT and GAT is still the best means of antibody detection and the NA genotype can be reliably determined by PCR‐SSP.
References
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Journal ArticleDOI
HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation.
Ole Olerup,Henrik Zetterquist +1 more
TL;DR: DR "low-resolution" typing by the PCR-SSP technique is ideally suited for analyzing small numbers of samples simultaneously and is an alternative to serological DR typing in routine clinical practice including donor-recipient matching in cadaveric transplantations.
Journal ArticleDOI
Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions.
Jeffrey V. Ravetch,B Perussia +1 more
TL;DR: Two nearly identical, linked genes that encode these transcripts have been cloned for Fc gamma RIII(CD16), one of which (III-1) is allelic for NA- 1 and NA-2, and the allelic sites have been mapped to two single nucleotides in the extracellular domain.
Journal ArticleDOI
Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination.
TL;DR: Comparison of the human and mouse genes generated a model for the evolutionary amplification of this locus, which established the structure of this complex locus.
Journal ArticleDOI
Sequences of complementary DNAs that encode the NA1 and NA2 forms of Fc receptor III on human neutrophils.
TL;DR: The amino acid substitutions and differences in the number of potential N-linked glycosylation sites probably account for the different forms of neutrophil FcR III observed after digestion with N-glycanase and for the antigenic heterogeneity of this receptor.
Journal Article
Neutrophil-specific antigens: immunology and clinical significance.
P Lalezari,E Radel +1 more