Journal ArticleDOI
Neonatal sepsis: A difficult diagnostic challenge
Francesco Raimondi,Teresa Ferrara,Rosalba Maffucci,Paola Milite,Dorothea Del Buono,Pasquale Santoro,Letizia Capasso,Ernesto Grimaldi +7 more
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TLDR
The investigatoruated the clinical usefulness of these morphologic parameters(also referred to as positional parameters) as possible indicators of an acute infectious process by analyzing themorphologic changes seen in the left-shifted and reactivesegmented neutrophils by using the Coulter LH 750 with VCS technology.About:
This article is published in Clinical Biochemistry.The article was published on 2011-05-01. It has received 28 citations till now. The article focuses on the topics: Neonatal sepsis & Absolute neutrophil count.read more
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Journal ArticleDOI
Salivary C-reactive protein, mean platelet volume and neutrophil lymphocyte ratio as diagnostic markers for neonatal sepsis.
TL;DR: This study provides support for further studies on the usefulness of salivary C-reactive protein, mean platelet volume, and neutrophil-lymphocyte ratio as diagnostic markers for neonatal sepsis.
Journal ArticleDOI
Can neutrophil to lymphocyte ratio predict late-onset sepsis in preterm infants?
TL;DR: The aim of this study was to evaluate the relationship between culture positiveness and NLR in cases where the reason of sepsis was considered, and to foresight an idea about the active agents.
Book ChapterDOI
Metabolomics in Newborns.
TL;DR: This review emphasizes the workflow of a typical metabolomics study and summarizes the latest results obtained in neonatal studies with particular interest in prematurity, intrauterine growth retardation, inborn errors of metabolism, perinatal asphyxia, sepsis, necrotizing enterocolitis, kidney disease, bronchopulmonary dysplasia, and cardiac malformation and dysfunction.
Journal ArticleDOI
Soluble CD14 subtype (sCD14-ST) presepsin in premature and full term critically ill newborns with sepsis and SIRS.
Michele Mussap,Elisabetta Puxeddu,Melania Puddu,Giovanni Ottonello,F. Coghe,Paola Comite,Francesco Cibecchini,Vassilios Fanos +7 more
TL;DR: It is found that sCD14-ST presepsin could be introduced in clinical practice as a diagnostic tool for improving the management of neonatal sepsis and non-bacterial SIRS and that in the population of babies with non-infectious SIRs, CRP and sCD 14-ST did not correlate with each other.
Journal ArticleDOI
New diagnostic possibilities in systemic neonatal infections: metabolomics.
Angelica Dessì,Giovanni Corsello,Mauro Stronati,Diego Gazzolo,Pierluigi Caboni,Roberta Carboni,Vassilios Fanos +6 more
TL;DR: In this paper, metabolomic analysis seems to be a promising method for determining metabolic variations correlated with systemic neonatal infections, however, there is still no single test that satisfies the criteria as being the ideal marker for the early diagnosis of neonatal sepsis.
References
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Journal ArticleDOI
Quantitative determination of neutrophil VCS parameters by the Coulter automated hematology analyzer: new and reliable indicators for acute bacterial infection.
TL;DR: A significant increase in the mean channel of neutrophil volume (MNV) from septic patients compared with control subjects was observed and it is believed that the MNV has a potential to be an additional indicator for acute bacterial infection.
Journal ArticleDOI
Quantitative Determination of Neutrophil VCS Parameters by the Coulter Automated Hematology Analyzer
TL;DR: It is believed that the MNV has a potential to be an additional indicator for acute bacterial infection and was present even in patients who did not have leukocytosis or neutrophilia.
Journal ArticleDOI
Neutrophil volume distribution width : A new automated hematologic parameter for acute infection
TL;DR: To investigate the value of the neutrophil volume distribution width (NDW), generated by VCS technology of the Coulter LH 750 hematology analyzer, as an additional predictor of acute infection, the NDW has potential for use as anAdditional indicator for diagnosing acute infection.