Journal ArticleDOI
Neuroimaging in Blast-Related Mild Traumatic Brain Injury.
TLDR
Vast variation in the sample, design, and measurement features across studies precludes salient conclusions regarding the effectiveness of neuroimaging to assess outcomes and elucidate pathomechanisms in blast-related mild traumatic brain injury.Citations
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Fluid biomarkers for mild traumatic brain injury and related conditions
Henrik Zetterberg,Kaj Blennow +1 more
TL;DR: The literature on fluid biomarkers for neuronal, axonal, oligodendrocytic, astroglial and blood–brain barrier injury, as well as markers for neuroinflammation and metabolic dysregulation, in the context of mild TBI, PCS and CTE are reviewed.
Journal ArticleDOI
Blast-Related Traumatic Brain Injury: Current Concepts and Research Considerations.
TL;DR: This review is aimed toward TBI researchers, as it covers important concepts and considerations for studying blast-induced head trauma, whether blast overpressure induces measureable biomarkers, and whether a biodosimeter can link blast exposure to health outcomes, using acute radiation exposure as a corollary.
Journal ArticleDOI
Eye tracking technology in sports-related concussion: a systematic review and meta-analysis.
TL;DR: Eye tracking technology in the acute injury phase holds promise in differentiating between athletes who have a concussion compared to those who do not, and therefore eye tracking technology may be a useful and sensitive screening and monitoring tool for sports-related concussions.
Journal ArticleDOI
Automated versus manual segmentation of brain region volumes in former football players
Jeffrey P. Guenette,Robert S. Stern,Yorghos Tripodis,Alicia S. Chua,Vivian Schultz,Valerie J. Sydnor,Nathaniel Somes,Sarina Karmacharya,Christian Lepage,Pawel Wrobel,Michael L. Alosco,Brett M. Martin,Christine E. Chaisson,Michael J. Coleman,Alexander P. Lin,Ofer Pasternak,Nikos Makris,Martha E. Shenton,Inga K. Koerte,Inga K. Koerte +19 more
TL;DR: Automated FreeSurfer segmentation of the corpus callosum, lateral ventricles, and amygdala-hippocampus complex may be appropriate for analysis without manual correction, but the amygdala, hippocampus, and cingulate gyrus need further manual correction prior to performing group comparisons and correlations with neurobehavioral measures.
Journal ArticleDOI
Blast-Exposed Veterans With Mild Traumatic Brain Injury Show Greater Frontal Cortical Thinning and Poorer Executive Functioning.
Alexandra L. Clark,Victoria C. Merritt,Erin D. Bigler,Katherine J. Bangen,Katherine J. Bangen,Madeleine L. Werhane,Madeleine L. Werhane,Scott F. Sorg,Scott F. Sorg,Mark W. Bondi,Mark W. Bondi,Dawn M. Schiehser,Dawn M. Schiehser,Lisa Delano-Wood,Lisa Delano-Wood +14 more
TL;DR: Findings show that Veterans with mTBI and BE may be at risk for cortical thinning post-deployment, and demonstrate that reductions in CT are associated with worse executive functioning among Veterans with high levels of cumulative BE.
References
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Journal ArticleDOI
AFNI: software for analysis and visualization of functional magnetic resonance neuroimages
TL;DR: A package of computer programs for analysis and visualization of three-dimensional human brain functional magnetic resonance imaging (FMRI) results is described and techniques for automatically generating transformed functional data sets from manually labeled anatomical data sets are described.
Journal ArticleDOI
Statistical parametric maps in functional imaging: A general linear approach
Karl J. Friston,Andrew P. Holmes,Keith J. Worsley,J-B. Poline,Chris D. Frith,Richard S. J. Frackowiak +5 more
TL;DR: In this paper, the authors present a general approach that accommodates most forms of experimental layout and ensuing analysis (designed experiments with fixed effects for factors, covariates and interaction of factors).
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Complex network measures of brain connectivity: uses and interpretations.
Mikail Rubinov,Olaf Sporns +1 more
TL;DR: Construction of brain networks from connectivity data is discussed and the most commonly used network measures of structural and functional connectivity are described, which variously detect functional integration and segregation, quantify centrality of individual brain regions or pathways, and test resilience of networks to insult.
Book
Higher cortical functions in man
TL;DR: Among the authors' patients was a bookkeeper with a severe form of sensory aphasia who could still draw up the annual balance sheet in spite of severe disturbances of speech and although he was unable to remember the names of his subordinates and used to refer to them incorrectly.
Journal ArticleDOI
Consensus statement on concussion in sport
Paul McCrory,Willem H. Meeuwisse,Mark Aubry,Bob Cantu,Jiří Dvořák,Ruben J. Echemendia,Lars Engebretsen,Karen M. Johnston,Jeffrey S. Kutcher,Martin Raftery,Allen Sills,Brian W. Benson,Gavin A Davis,Richard G. Ellenbogen,Kevin M. Guskiewicz,Stanley A. Herring,Grant L. Iverson,Barry D. Jordan,James Kissick,Michael McCrea,Andrew S. McIntosh,David Maddocks,Michael Makdissi,Laura Purcell,Margot Putukian,Kathryn J Schneider,Charles H. Tator,Michael Turner +27 more
TL;DR: This paper is a revision and update of the recommendations developed following the 1st (Vienna 2001), 2nd (Prague 2004) and 3rd (Zurich 2008) International Consensus Conferences on Concussions in Sport and is based on the deliberations at the 4th International Conference on Concussion in Sport held in Zurich, November 2012.