Nothing tastes as good as skinny feels: the neurobiology of anorexia nervosa
Walter H. Kaye,Christina E. Wierenga,Ursula F. Bailer,Ursula F. Bailer,Alan N. Simmons,Alan N. Simmons,Amanda Bischoff-Grethe +6 more
TLDR
Brain imaging studies suggest that altered eating is a consequence of dysregulated reward and/or awareness of homeostatic needs, perhaps related to enhanced executive ability to inhibit incentive motivational drives.About:
This article is published in Trends in Neurosciences.The article was published on 2013-02-01 and is currently open access. It has received 398 citations till now. The article focuses on the topics: Anorexia nervosa (differential diagnoses) & Eating disorders.read more
Citations
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Anorexia nervosa: aetiology, assessment, and treatment
Stephan Zipfel,Katrin Elisabeth Giel,Katrin Elisabeth Giel,Cynthia M. Bulik,Cynthia M. Bulik,Phillipa Hay,Ulrike Schmidt +6 more
TL;DR: To successfully fight this enigmatic illness, understanding of the underlying biological and psychosocial mechanisms has to be enhanced, strategies for prevention and early intervention improved, and treatments targeted through improved understanding of specific disease mechanisms targeted.
Journal ArticleDOI
Adolescent Eating Disorders: Update on Definitions, Symptomatology, Epidemiology, and Comorbidity
TL;DR: A detailed description is given of the symptomatology of each eating disorder that typically manifests during adolescence, and new developments in classification issues resulting from the transition to DSM-5 are reviewed.
Journal ArticleDOI
Eating Disorders in Children and Adolescents: State of the Art Review
Kenisha Campbell,Rebecka Peebles +1 more
TL;DR: Outpatient family-based treatment focused on weight restoration, reducing blame, and empowering caregivers has emerged as particularly effective; cognitive behavioral therapy, individual therapy, and higher levels of care may also be appropriate.
Relation Between Obesity and Blunted Striatal Response to Food Is Moderated by TaqIA A1 Allele
Michelle D. Wang,H. Yin,R. Landick,J. Gelles,L. S. Churchman,Z. Okten,R. S. Rock,J. F. Dawson,J. A. Spudich,C. G. Baumann,S. B. Smith,V. A. Bloomfield,C. Bustamante,A. R. Dunn,D. R. Halpin,D. Herschlag,W. L. Martin,B. H. Robinson,J. M. Schurr,A. L. Smith,R. M. Weisinger,S. J. Wrenn,Y. Bai,S. Doniach,K. Ito,J. Lipfert,I. S. Millett,S. Seifert,P. Thiyagarajan,H. Tsuruta +29 more
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Can Interoception Improve the Pragmatic Search for Biomarkers in Psychiatry
TL;DR: It is concluded that interoception represents a viable avenue for clinical and translational research in psychiatry, with a well-established conceptual framework, a neural basis, measurable biomarkers, interdisciplinary appeal, and transdiagnostic targets for understanding and improving mental health outcomes.
References
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Separate Neural Systems Value Immediate and Delayed Monetary Rewards
TL;DR: The authors examined the neural correlates of time discounting while subjects made a series of choices between monetary reward options that varied by delay to delivery and demonstrated that two separate systems are involved in such decisions.
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Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex
Rita Z. Goldstein,Nora D. Volkow +1 more
TL;DR: An integrated model of drug addiction that encompasses intoxication, bingeing, withdrawal, and craving is proposed, and results imply that addiction connotes cortically regulated cognitive and emotional processes, which result in the overvaluing of drug reinforcers, the undervalued of alternative rein forcers, and deficits in inhibitory control for drug responses.
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The role of the basal ganglia in habit formation
Henry H. Yin,Barbara J. Knowlton +1 more
TL;DR: Recent work combining modern behavioural assays and neurobiological analysis of the basal ganglia has begun to yield insights into the neural basis of habit formation.
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Neurobiology of emotion perception I: the neural basis of normal emotion perception
TL;DR: It is suggested that the extent to which a stimulus is identified as emotive and is associated with the production of an affective state may be dependent upon levels of activity within these two neural systems.