Journal ArticleDOI
Nuclear relaxation in macromolecules by paramagnetic ions: a novel mechanism
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TLDR
In this article, the effect of the magnetic dipolar interaction of a nuclear spin with the thermal average of an electronic spin (Curie spin) is modulated by molecular motion but not by the electronic spin relaxation.About:
This article is published in Journal of Magnetic Resonance.The article was published on 1975-07-01. It has received 308 citations till now. The article focuses on the topics: Spin polarization & Spin–lattice relaxation.read more
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Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications
Sophie Laurent,Delphine Forge,Marc Port,Alain Roch,Caroline Robic,Luce Vander Elst,Robert N. Muller +6 more
TL;DR: Practical Interests of Magnetic NuclearRelaxation for the Characterization of Superparamagnetic Colloid, and Use of Nanoparticles as Contrast Agents forMRI20825.
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Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field
TL;DR: It is shown that the increase in T-1(2) with increasing blood deoxygenation arises from diffusion of water through these field gradients, which increases the volume magnetic susceptibility within the erythrocytes and thus creates local fieldgradients around these cells.
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Magnetic Nanoparticles: Surface Effects and Properties Related to Biomedicine Applications
TL;DR: The magnetic properties of nanoparticles which are directly related to their applications in biomedicine are discussed, mainly on surface effects and ferrite nanoparticles, and on one diagnostic application of magnetic nanoparticles as magnetic resonance imaging contrast agents.
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Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers
TL;DR: This comprehensive review describes the state of the art of clinically approved contrast agents, their mechanism of action, and factors influencing their safety and efforts to make safer contrast agents either by increasing relaxivity, increasing resistance to metal ion release, or by moving to gadolinium(III)-free alternatives.
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Theory, Practice, and Applications of Paramagnetic Relaxation Enhancement for the Characterization of Transient Low-Population States of Biological Macromolecules and Their Complexes
G. Marius Clore,Junji Iwahara +1 more
TL;DR: This work has shown that highly populated states are located within the global free energy minimum region of a relatively rough free energy hypersurface, and the structure and dynamics of lowly populated, higher free energy states which cannot be modeled.
References
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Journal ArticleDOI
Relaxation Effects in Nuclear Magnetic Resonance Absorption
TL;DR: In this article, the authors studied the effect of the thermal motion of the magnetic nuclei upon the spin-spin interaction in a rigid lattice and the line width of the absorption line.
Journal ArticleDOI
Relaxation Processes in a System of Two Spins
TL;DR: Abragam and Pound's method for the calculation of the longitudinal relaxation time was extended to the transverse relaxation time in this paper, which gave rise to a steady and transient Overhauser effect.
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Proton Relaxation Times in Paramagnetic Solutions. Effects of Electron Spin Relaxation
N. Bloembergen,L. O. Morgan +1 more
TL;DR: In this article, it was shown that the distortion of the hydrated complex by collisions with other water molecules is responsible for the decrease in T2 in Mn++ (and other) solutions in very high magnetic fields.
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Proton Relaxation Times in Paramagnetic Solutions
TL;DR: In this paper, an exchange interaction between the electron spin and proton spin in adjacent water molecules in paramagnetic solutions was proposed, and an explanation was given why T1/T2 for protons is much larger than unity in solutions of these particular ions in high magnetic fields, whereas T1 is about equal to T2 in other solutions or in low fields.