Journal ArticleDOI
On the67Ga-binding acid mucopolysaccharide in malignant tumor
TLDR
In this article, the structure of 67Ga-binding acid mucopolysaccharide in tumor tissues was determined from measuring neutral saccharides in the structure, and it was determined that the principal acid acid acid in the tumor was either keratan sulfate and/or keratan polysulfate.Abstract:
The present study was undertaken to determine the structure of67Ga-binding acid mucopolysaccharide in tumor tissues. It was determined from measuring neutral saccharide in the structure that the principal67Ga-binding acid mucopolysaccharide in the tumor was keratan sulfate and/or keratan polysulfate. On the other hand, it was clarified from the results of mucopolysaccharase treatment that the main67Ga-binding acid mucopolysaccharide in tumor was not keratan sulfate, heparan sulfate, heparin, nor chondroitin sulfate A, B, or C. Based on the present results, it was deduced that the main67Ga-binding acid mucopolysaccharide in tumor is keratan polysulfate and that this acid mucopolysaccharide plays the most important role in tumor accumuation of67Ga.read more
Citations
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Journal ArticleDOI
67Ga accumulation in inflammatory lesion and its mechanism: Comparison with malignant tumor
Atsushi Ando,Kazuo Nitta,Itsuko Ando,Shogo Katsuda,Norihisa Tonami,Tatsunosuke Hiraki,Kinichi Hisada,Hiroshi Ogawa +7 more
TL;DR: It is clear from this study that 67Ga is avidly accumulated in areas where the subcutanous tissue is infiltrated with neutrophil and macrophages, that it is not accumulated at the sites in which neutrophils are crowded, that nuclear material, mitochondria, lysosomes and microsomes do not play a major role in 67Ga accumulation in the lesion.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids.
Journal ArticleDOI
Studies on yeast metabolism. 1. Fractionation and microdetermination of cell carbohydrates
W. E. Trevelyan,J. S. Harrison +1 more
TL;DR: Direct measurement of the metabolic changes in the intracellular carbohydrate of yeast has usually been restricted to the determination of total hydrolysable carbohydrate, that is to say, of reducing power after acid hydrolysis of a cell suspension.
Journal ArticleDOI
A method for the separation of acid mucopolysaccharides: its application to the isolation of heparin from the skin of rats.
TL;DR: The present communication describes a procedure for quantitative separation of small quantities of hyaluronic acid, chondroitinsulfuric acids, and heparin and its application to a study of the mucopolysaccharides of skin.
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