Journal ArticleDOI
One-step synthesis of substituted 6-amino-5-cyanospiro-4-(piperidine-4')- 2H,4H-dihydropyrazolo[3,4-b]pyrans.
Anatoliy M. Shestopalov,Yuliya M. Emeliyanova,Aleksandr A. Shestopalov,Lyudmila A. Rodinovskaya,Zukhra I. Niazimbetova,Dennis H. Evans +5 more
TLDR
Three-component condensation of 4-piperidinones, 5-pyrazolones, and malononitrile proceeds chemically and electrochemically and is a convenient one-step means of synthesis of substituted 6-amino-5-cyanospiro-4-(piperidine-4')-2H,4H-dihydropyrazolo[3,4-b]pyrans.About:
This article is published in Organic Letters.The article was published on 2002-02-07. It has received 115 citations till now. The article focuses on the topics: Malononitrile & Piperidine.read more
Citations
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Utilisation of 1,3‐Dicarbonyl Derivatives in Multicomponent Reactions
TL;DR: In this article, an overview of the potential of 1,3-dicarbonyl derivatives for the selective construction of highly functionalised small organic molecules of high synthetic and biological value is presented.
Journal ArticleDOI
Recent developments in solvent-free multicomponent reactions: a perfect synergy for eco-compatible organic synthesis
TL;DR: In this paper, the authors summarized the results reported mainly within the last 10 years, and it is quite clear from the growing number of emerging publications in this field that the possibility to utilize multicomponent technology allows reaction conditions to be accessed that are very valuable for organic synthesis.
Journal ArticleDOI
Efficient one-pot synthesis of spirooxindole derivatives catalyzed by L-proline in aqueous medium.
TL;DR: An efficient one-pot synthesis of spirooxindole derivatives by three-component reaction of isatins, malononitrile and 1,3-dicarbonyl compounds in water in the presence of l-proline is reported.
Journal ArticleDOI
A novel microwave-mediated one-pot synthesis of indolizines via a three-component reaction.
TL;DR: The microwave-mediated three-component reaction of acyl bromide, pyridine, and acetylene is catalyzed by basic alumina to give corresponding indolizines in excellent yields in a one-pot reaction.
Journal ArticleDOI
Sodium bromide catalysed one-pot synthesis of tetrahydrobenzo[b]pyrans via a three-component cyclocondensation under microwave irradiation and solvent free conditions
Ipsita Devi,Pulak J. Bhuyan +1 more
TL;DR: Sodium bromide catalysed three-component cyclocondensation of aryl aldehydes, alkyl nitriles and dimedone proceeds under microwave irradiation in solvent free conditions to give highly functionalised tetrahydrobenzo[b]pyrans in excellent yields as discussed by the authors.
References
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Synthesen mit Nitrilen, XXXV. Reaktionen von Tetracyanäthylen mit Heterocyclen
Hans Junek,H. Aigner +1 more
TL;DR: The reaction of tetracyanoethylene with barbituric acids yields tetrahydro-2H-pyrano[2.3-d]-pyrimidines or dipyrimidinylmalonodinitriles (3a, b) depending on the reaction temperature.
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A New Route to 4H‐Pyrano[2,3‐c]pyrazoles
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Electrogeneration of the anion of ethyl nitroacetate and its use in electroorganic synthesis
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Electrochemical reduction of acids in dimethyl sulfoxide. Comparison of weak C–H, N–H and O–H acids
TL;DR: In this paper, the reduction of 21 weak acids, HA, has been studied in dimethyl sulfoxide and their p K a (DMSO) values ranged from 6.4 to 19.8.