Orthosiphon stamineus Benth. is an Outstanding Food Medicine: Review of Phytochemical and Pharmacological Activities.
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TLDR
This review is a comprehensive summary of the presently available chemical, pharmacological investigations as well as the traditional and therapeutic uses of O. stamineus, a valued medicinal plant in traditional folk medicine.Abstract:
Orthosiphon stamineus Benth. (Lamiaceae) is a valued medicinal plant in traditional folk medicine. Many pharmacological studies have demonstrated the ability of this plant to exhibit antimicrobial, antioxidant, hepatoprotection, antigenotoxic, antiplasmodial, cytotoxic, cardioactive, antidiabetic, anti-inflammatory activies. This review is a comprehensive summary of the presently available chemical, pharmacological investigations as well as the traditional and therapeutic uses of this plant. Important and different experimental data have been addressed along with a review of all phytochemicals identified in this plant, including flavonoids, terpenoids, and essential oils. O. stamineus has wide traditional and pharmacological uses in various pathophysiological conditions. Therefore, it is an attractive subject for further experimental and clinical investigations.read more
Citations
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"Kidney Tea" and Its Bioactive Secondary Metabolites for Treatment of Gout.
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Sinensetin: An Insight on Its Pharmacological Activities, Mechanisms of Action and Toxicity.
TL;DR: Sinensetin, a plant derived polymethoxylated flavonoid found in Orthosiphon aristatus var. aristatus and several citrus fruits, has been found to possess strong anticancer activities and a variety of other pharmacological benefits and promising potency in intended activities with minimal toxicity.
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Evaluating Traditional Chinese Medicine and Herbal Products for the Treatment of Gestational Diabetes Mellitus.
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Genotype selection for phytochemical content and pharmacological activities in ethanol extracts of fifteen types of Orthosiphon aristatus (Blume) Miq. leaves using chemometric analysis.
TL;DR: The genotypes A1, A2, A7, A11, and A15 were identified as superior based on their phytochemicals content and pharmacological activities coupled with chemometric analysis.
References
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The effects of different extraction solvents of varying polarities on polyphenols of Orthosiphon stamineus and evaluation of the free radical-scavenging activity
TL;DR: In this paper, a leaf powder of Orthosiphon stamineus was extracted with the following solvents; distilled water, 50% aqueous methanols, methanol, 70% acyclic acid, and chloroform at 2, 4 and 8 h, respectively, on a water bath at 40 °C.
Journal ArticleDOI
The Emerging Multifaceted Roles of Nitric Oxide
Paul C. Kuo,Rebecca A. Schroeder +1 more
TL;DR: This review is an attempt to acquaint the surgical community with the fundamentals of NO biochemistry and physiology and to enable physicians to better understand these disease processes and utilize new pharmacologic therapies.
Journal ArticleDOI
Constituents of the Vietnamese Medicinal Plant Orthosiphon stamineus
Yasuhiro Tezuka,Pavlos Stampoulis,Arjun H. Banskota,Suresh Awale,Kim Qui Tran,Ikuo Saiki,Shigetoshi Kadota +6 more
TL;DR: All the isolated compounds were tested for their cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, and the new diterpenes, except for 4, and flavonoids showed cytot toxicity with an ED50 value between 10 and 90 microg/ml.
Journal Article
Effect of ethanol concentration, extraction time and extraction temperature on the recovery of phenolic compounds and antioxidant capacity of Orthosiphon stamineus extracts
K.K. Chew,K.K. Chew,M.Z. Khoo,M.Z. Khoo,S.Y. Ng,S.Y. Ng,Yin Yin Thoo,Yin Yin Thoo,Wan Aida Wan Mustapha,Wan Aida Wan Mustapha,Chun Wai Ho,Chun Wai Ho +11 more
TL;DR: In this paper, the authors investigated the effects of ethanol concentration (0-100%, v/v), extraction time (60-300 min), and extraction temperature (25-65oC) on the phenolic recovery using single factor experiment.
Journal ArticleDOI
Sinensetin, eupatorin, 3′-hydroxy-5, 6, 7, 4′-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of Orthosiphon stamineus from Malaysia
TL;DR: An HPLC method was developed for the separation and determination of three methoxylated flavones:sinensetin (SEN), eupatorin (EUP) and 3 " -hydroxy-5,6,7,4 " -tetramethoxyflavone (TMF) and rosmarinic acid (RA), a caffeic acid derivative in Orthosiphon stamineus (OS) as discussed by the authors.