Journal ArticleDOI
Outcome after introduction of complete mesocolic excision for colon cancer is similar for open and laparoscopic surgical treatments.
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TLDR
There was no survival difference between open and laparoscopic CME colonic resections, and the present OS improved from a previous OS from 2000, while the surgical approach was not a significant predictor for any of the survival parameters.Abstract:
Background: Complete mesocolic excision (CME) and a high (apical) vascular tie may improve oncologic outcome after surgery for colon cancer. Our primary aim was tread more
Citations
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Disease-free survival after complete mesocolic excision compared with conventional colon cancer surgery: a retrospective, population-based study
Claus Anders Bertelsen,Anders Ulrich Neuenschwander,Jens Erik Jansen,Michael Wilhelmsen,Anders Kirkegaard-Klitbo,Jutaka Reilin Tenma,Birgitte Bols,Peter Ingeholm,Leif Ahrenst Rasmussen,Lars V. Jepsen,Else Refsgaard Iversen,Bent Kristensen,Ismail Gögenur +12 more
TL;DR: It is indicated that CME surgery is associated with better disease-free survival than is conventional colon cancer resection for patients with stage I-III colon adenocarcinoma.
Journal ArticleDOI
The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery : proceedings of a consensus conference.
Karl Søndenaa,Karl Søndenaa,Philip Quirke,Werner Hohenberger,Kenichi Sugihara,Hirotoshi Kobayashi,Hermann Kessler,Gina Brown,V. Tudyka,André D'Hoore,Robin H. Kennedy,Nicholas P. West,Seon Hahn Kim,Richard J. Heald,Kristian Eeg Storli,Arild Nesbakken,Brendan J. Moran +16 more
TL;DR: There are sound oncological hypotheses for a more radical approach than has been common up to now to colon cancer resection, however, this may not necessarily apply in early stages of the tumour stage.
Journal ArticleDOI
Short‐term outcomes after complete mesocolic excision compared with ‘conventional’ colonic cancer surgery
Claus Anders Bertelsen,Anders Ulrich Neuenschwander,Jens Erik Jansen,Anders Kirkegaard-Klitbo,Jutaka Reilin Tenma,Michael Wilhelmsen,Leif Ahrenst Rasmussen,Lars V. Jepsen,Bent Kristensen,Ismail Gögenur +9 more
TL;DR: Complete mesocolic excision seems to be associated with improved oncological outcomes compared with ‘conventional’ surgery, but there is a potential for higher morbidity.
Journal ArticleDOI
Surgery along the embryological planes for colon cancer: a systematic review of complete mesocolic excision
Nikolaos Gouvas,Christos Agalianos,Kleio Papaparaskeva,Aristotelis Perrakis,Werner Hohenberger,Evaghelos Xynos +5 more
TL;DR: There is strong evidence that CME offers a longer central pedicle that contains more lymph nodes than conventional surgery for colon cancer, and there is limited evidence that colectomy in terms of CME leads to improved long-term oncological outcomes.
Journal ArticleDOI
Open compared with laparoscopic complete mesocolic excision with central lymphadenectomy for colon cancer: a systematic review and meta-analysis.
TL;DR: The aim of this study was to compare the safety and efficacy of open and laparoscopic approaches for ELTs in colon cancer.
References
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Journal ArticleDOI
Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial
Antonio M. Lacy,Juan Carlos García-Valdecasas,Salvadora Delgado,Antoni Castells,Pilar Taura,Josep M. Piqué,Josep Visa +6 more
TL;DR: LAC is more effective than OC for treatment of colon cancer in terms of morbidity, hospital stay, tumour recurrence, and cancer-related survival.
Journal ArticleDOI
Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group.
David G. Jayne,Pierre J. Guillou,H. Thorpe,Philip Quirke,Joanne Copeland,Adrian Smith,Richard M. Heath,Julia Brown +7 more
TL;DR: Long-term outcomes for patients with rectal cancer were similar in those undergoing abdominoperineal resection and AR, and support the continued use of laparoscopic surgery in these patients.
Journal ArticleDOI
Standardized surgery for colonic cancer: complete mesocolic excision and central ligation--technical notes and outcome.
TL;DR: This technique is focused on an intact package of the tumour and its main lymphatic drainage and this technique is nowadays accepted worldwide for optimal rectal cancer surgery.
Journal ArticleDOI
Guidelines 2000 for Colon and Rectal Cancer Surgery
Heidi Nelson,Nicholas J. Petrelli,Arthur M. Carlin,Jean Couture,James W. Fleshman,Jose G. Guillem,Brent W. Miedema,David M. Ota,Daniel J. Sargent +8 more
TL;DR: A panel of experts reviewed current literature on oncologic resection techniques for level of evidence and grade of recommendation to draft guidelines that provide uniform definitions, principles, and practices and reports surgical guidelines and definitions based on the best available evidence.
Journal ArticleDOI
Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial.
M. Buunen,R. Veldkamp,Wim C. J. Hop,Esther Kuhry,Johannes Jeekel,Eva Haglind,Lars Påhlman,Miguel A. Cuesta,Simon Msika,Mario Morino,Antonio M. Lacy,Hendrik J. Bonjer +11 more
TL;DR: The trial could not rule out a difference in disease-free survival at 3 years in favour of open colectomy because the upper limit of the 95% CI for the difference just exceeded the predetermined non-inferiority boundary of 7%, but, it believes, clinically acceptable, justifying the implementation of laparoscopic surgery into daily practice.