Journal ArticleDOI
Palladium-catalyzed decarboxylative cross-coupling reaction between heteroaromatic carboxylic acids and aryl halides.
TLDR
A full overview of the decarboxylative cross-coupling reaction between heteroaromatic carboxylic acids and aryl halides is described, with palladium catalysts with short reaction times providing facile synthesis of aryL-substituted heterOaromatics.Abstract:
A full overview of the decarboxylative cross-coupling reaction between heteroaromatic carboxylic acids and aryl halides is described This transformation employs palladium catalysts with short reaction times providing facile synthesis of aryl-substituted heteroaromatics The effect of each reaction parameter including solvent, base, and additive employed as well as the full substrate scope of this transformation are reported Mechanistic evidence is also disclosed that sheds light on possible reaction pathwaysread more
Citations
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Decarboxylative coupling reactions: a modern strategy for C–C-bond formation
Nuria Rodríguez,Lukas J. Goossen +1 more
TL;DR: This critical review examines transition metal-catalyzed decarboxylative couplings that have emerged within recent years as a powerful strategy to form carbon-carbon or carbon-heteroatom bonds starting from carboxylic acids.
Journal ArticleDOI
Carboxylates as sources of carbon nucleophiles and electrophiles: comparison of decarboxylative and decarbonylative pathways
TL;DR: In this article, a comparison between the concepts of catalytic decarboxylative and decarbonylative couplings for the ipso-substitution of carboxylate groups, and illustrates their potential benefits over alternative C-C bond-forming reactions.
Journal ArticleDOI
Cross‐Coupling of Heteroarenes by CH Functionalization: Recent Progress towards Direct Arylation and Heteroarylation Reactions Involving Heteroarenes Containing One Heteroatom
TL;DR: In this article, a critical review with 430 references covers the results obtained in the period January 2009 to February 2013 in the area of the transition metal-catalyzed direct inter- and intramolecular (hetero)arylation reactions of heteroarenes containing one heteroatom.
Journal ArticleDOI
Transition-Metal-Mediated Cleavage and Activation of C–C Single Bonds
TL;DR: In this paper, the fundamental reactions for C-C single bond activation and cleavage mediated by transition metal complexes are reviewed in terms of their mechanisms, their intrinsic problems, and their published examples.
Journal ArticleDOI
Recent Progress in Coupling of Two Heteroarenes
TL;DR: The general purpose of this review is to give an exhaustive and clear picture in heteroaryl-heteroaryl bond formation as well as its application in the synthesis of natural products, pharmaceuticals, catalyst ligands, and materials.
References
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Journal ArticleDOI
Palladium-catalyzed cross-coupling reactions of organoboron compounds
Norio Miyaura,Akira Suzuki +1 more
TL;DR: In this paper, a cross-coupling reaction is proposed for coupling 1 -Alkenylboron Derivatives: Synthesis of Conjugated Dienes 6.
BookDOI
Metal-catalyzed cross-coupling reactions
TL;DR: In this paper, the authors present an approach to the formation of C-X (X = N, O, S) bonds in metal-catalyzed cross-coupling reactions.
Journal ArticleDOI
The Palladium‐Catalyzed Cross‐Coupling Reactions of Organotin Reagents with Organic Electrophiles [New Synthetic Methods (58)]
TL;DR: The cross-coupling of organotin reagents with a variety of organic electrophiles, catalyzed by palladium, provides a novel method for generating a carbon-carbon bond.
BookDOI
Handbook of organopalladium chemistry for organic synthesis
TL;DR: Palladium-CATALYZED Reactions Involving Nucleophilic Attack on -Ligands of Palladium-Alkene, PalladiumAlkyne, and Related Derivatives as mentioned in this paper.
Journal ArticleDOI
C-H Bond Functionalization in Complex Organic Synthesis
Kamil Godula,Dalibor Sames +1 more
TL;DR: In this paper, the functionalization of C-H bonds in complex organic substrates catalyzed by transition metal catalysts is studied and the key concepts and approaches aimed at achieving selectivity in complex settings are discussed.
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