Pathologic assessment of vasculopathies in pulmonary hypertension.
Giuseppe G. Pietra,Frédérique Capron,Susan Stewart,Ornella Leone,Marc Humbert,Ivan M. Robbins,Lynne Reid,Rubin M. Tuder +7 more
TLDR
A histopathological classification is proposed that includes both the predominant segment of the pulmonary vasculature affected and the possible coexistence of pathological changes in other vascular segments in PAH.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2004-06-16 and is currently open access. It has received 676 citations till now. The article focuses on the topics: Pulmonary Veno-Occlusive Disease & Pulmonary hypertension.read more
Citations
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Journal ArticleDOI
Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
Nazzareno Galiè,Marius M. Hoeper,Marc Humbert,Adam Torbicki,Jean-Luc Vachiery,J.A. Barberà,Maurice Beghetti,Paul A. Corris,Sean Gaine,J S R Gibbs,Miguel Ángel Gómez-Sánchez,Guillaume Jondeau,Walter Klepetko,Christian Opitz,Andrew J. Peacock,LJ Rubin,Michael J. Zellweger,Gérald Simonneau +17 more
TL;DR: In this paper, a review of the published evidence for management and/or prevention of a given condition is carried out by experts in the field and a critical evaluation of diagnostic and therapeutic procedures is performed including assessment of the risk/benefit ratio.
Journal ArticleDOI
Special article2015 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension
Nazzareno Galiè,Marc Humbert,Jean-Luc Vachiery,Simon Gibbs,Irene Lang,Adam Torbicki,Gérald Simonneau,Andrew J. Peacock,Anton Vonk Noordegraaf,Maurice Beghetti,Ardeschir Ghofrani,Miguel Angel Gomez Sanchez,Georg Hansmann,Walter Klepetko,Patrizio Lancellotti,Marco Matucci,Theresa McDonagh,Luc Pierard,Marius M. Hoeper +18 more
TL;DR: This article is being published concurrently in the European Heart Journal and the European Respiratory Journal and is identical except for minor stylistic and spelling differences in keeping with each journal’s style.
Journal ArticleDOI
[2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension].
Nazzareno Galiè,Marc Humbert,Jean-Luc Vachiery,Simon Gibbs,Irene Lang,Adam Torbicki,Gérald Simonneau,Andrew J. Peacock,Anton Vonk Noordegraaf,Maurice Beghetti,Ardeschir Ghofrani,Miguel Angel Gomez Sanchez,Georg Hansmann,Walter Klepetko,Patrizio Lancellotti,Marco Matucci,Theresa McDonagh,Luc Pierard,Pedro T. Trindade,Maurizio Zompatori,Marius M. Hoeper +20 more
TL;DR: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS) is constituted.
Journal ArticleDOI
ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension: A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: Developed in Collaboration With the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association
Vallerie V. McLaughlin,Stephen L. Archer,David B. Badesch,Robyn J. Barst,Harrison W. Farber,Jonathan R. Lindner,Michael A. Mathier,Michael D. McGoon,Myung H. Park,Robert S. Rosenson,Lewis J. Rubin,Victor F. Tapson,John Varga +12 more
TL;DR: In this paper, the authors discuss the role of the chairperson of FAHA and the chair's role in the FAHA Board of Trustee selection process and propose a new chairperson for FAHA.
Journal ArticleDOI
Clinical classification of pulmonary hypertension
Gérald Simonneau,Nazzareno Galiè,Lewis J. Rubin,David Langleben,Werner Seeger,Guido Domenighetti,Simon Gibbs,Didier Lebrec,Rudolf Speich,Maurice Beghetti,Stuart Rich,Alfred P. Fishman +11 more
TL;DR: The growth of understanding of the pulmonary hypertensive diseases that has enabled the development of a clinical classification oriented towards prevention and treatment is traced.
References
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Pulmonary arterial hypertension.
TL;DR: There is no cure for pulmonary arterial hypertension but several novel therapeutic options are now available that can improve symptoms and increase survival.
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Pulmonary vascular lesions occurring in patients with chronic major vessel thromboembolic pulmonary hypertension.
Kenneth M. Moser,Colin M. Bloor +1 more
TL;DR: Primary pulmonary hypertension cannot be differentiated from potentially correctable CTEPH on the basis of histopathologic findings in small pulmonary arteries, and development of these hypertensive changes may explain the deterioration which these patients experience preoperatively over time.
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Mature vascular endothelium can give rise to smooth muscle cells via endothelial-mesenchymal transdifferentiation: in vitro analysis.
TL;DR: In vitro data show that mature bovine systemic and pulmonary endothelium contains cells that can acquire a SM phenotype via a transdifferentiation process that is transforming growth factor-&bgr;1– and cell-cell contact–dependent, but proliferation-independent.
Journal ArticleDOI
Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension.
S.D. Lee,Kenneth R. Shroyer,Neil E. Markham,Carlyne D. Cool,Norbert F. Voelkel,Rubin M. Tuder +5 more
TL;DR: The data of a frequent monoclonal endothelial cell proliferation in PPH suggests that a somatic genetic alteration similar to that present in neoplastic processes may be responsible for the pathogenesis of PPH.
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Treatment of pulmonary hemangiomatosis with recombinant interferon alfa-2a.
TL;DR: In this paper, the authors describe a patient with pulmonary hemangiomatosis who presented with digital clubbing and bilateral interstitial pulmonary disease, and they used interferon alfa-2a for 14 months.
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