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Journal ArticleDOI

Pecularities of sterol biosynthesis in plants

Guy Ourisson
- 01 Apr 1994 - 
- Vol. 143, pp 434-439
TLDR
Higher plants are in particular characterized by the intermediacy, in their biosynthetic pathway towards sterols, of cycloartenol (instead of lanosterol, the first tetracylic intermediate in animals and fungi), which is interpreted in evolutionary terms as indicative of a primitive state.
About
This article is published in Journal of Plant Physiology.The article was published on 1994-04-01. It has received 26 citations till now. The article focuses on the topics: Cycloartenol & Lanosterol.

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Citations
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Journal ArticleDOI

Sterols in microorganisms.

TL;DR: This review describes the variety of sterol structures found in microalgae, yeasts, fungi, protozoans and microheterotrophs, and possible application areas for sterols derived from mass culture of micro algae and other microorganisms are highlighted.
Journal ArticleDOI

Biosynthesis of cholesterol and other sterols.

TL;DR: Cholesterol and its relatives possessing the 1,2-cyclopentanoperhydrophenanthrene ring system as mentioned in this paper form the sterolome, which comprises a chemical library of more than 1000 natural products found in all forms of eukaryotes and some prokaryotes that serve a myriad of biological functions.
Journal ArticleDOI

The role of sterols in plant growth and development.

TL;DR: The characterization of genes encoding sterol biosynthetic enzymes and the isolation of novel plant lines affected in the expression of those genes have shed new light on the involvement of sterols in biological processes such as embryonic development, cell and plant growth, and fertility.
Journal ArticleDOI

FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis

TL;DR: It is proposed that synthesis of sterol signals in addition to BRs is important in mediating regulated cell growth and organization during embryonic development and indicates a novel role for sterols in the embryogenesis of plants.
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Expression of the Hevea brasiliensis (H.B.K.) Mull. Arg. 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase 1 in Tobacco Results in Sterol Overproduction.

TL;DR: Transgenic lines showed an increase in the level of total sterols up to 6-fold, probably because of an increased expression level of hmg1 mRNA and a corresponding increased enzymatic activity for HMGR, which strongly support the conclusion that plant HMGR is a key limiting enzyme in phytosterol biosynthesis.
References
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Book

The Neutral Theory of Molecular Evolution

Motoo Kimura
TL;DR: The neutral theory as discussed by the authors states that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants, which has caused controversy ever since.

The neutral theory of molecular evolution.

Motoo Kimura
TL;DR: The neutral theory as mentioned in this paper states that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants, which has caused controversy ever since.
Journal ArticleDOI

Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate.

TL;DR: Results confirmed the earlier results obtained by incorporation of 13C-labelled acetate into the hopanoids of other bacteria and led to the identification of a novel biosynthetic route for the early steps of isoprenoid biosynthesis.
Journal ArticleDOI

Sterol structure and membrane function.

TL;DR: In this paper, Sterol, Structure and Membrane Function (SSTF) is used to describe the structure and function of Membranes in the human brain. Critical Reviews in Biochemistry: Vol. 14, No. 1, pp. 47-92.
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