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Performance standards for antimicrobial susceptibility testing
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TLDR
The supplemental information presented in this document is intended for use with the antimicrobial susceptibility testing procedures published in the following Clinical and Laboratory Standards Institute (CLSI)–approved standards.Abstract:
The supplemental information presented in this document is intended for use with the antimicrobial susceptibility testing procedures published in the following Clinical and Laboratory Standards Institute (CLSI)–approved standards: M02-A12—Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard—Twelfth Edition; M07-A10—Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard—Tenth Edition; and M11-A8—Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria; Approved Standard— Eighth Edition. The standards contain information about both disk (M02) and dilution (M07 and M11) test procedures for aerobic and anaerobic bacteria. Clinicians depend heavily on information from the microbiology laboratory for treatment of their seriously ill patients. The clinical importance of antimicrobial susceptibility test results demands that these tests be performed under optimal conditions and that laboratories have the capability to provide results for the newest antimicrobial agents. The tabular information presented here represents the most current information for drug selection, interpretation, and QC using the procedures standardized in the most current editions of M02, M07, and M11. Users should replace the tables published earlier with these new tables. (Changes in the tables since the previous edition appear in boldface type.) Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing. 26th ed. CLSI supplement M100S (ISBN 1-56238-923-8 [Print]; ISBN 1-56238924-6 [Electronic]). Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087 USA, 2016. The data in the interpretive tables in this supplement are valid only if the methodologies in M02-A12—Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard—Twelfth Edition; M07-A10—Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard—Tenth Edition; and M11-A8—Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria; Approved Standard— Eighth Edition are followed.read more
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Journal ArticleDOI
Metallo-β-Lactamase-Producing Gram-Negative Bacilli: Laboratory-Based Surveillance in Cooperation with 13 Clinical Laboratories in the Kinki Region of Japan
Hisaaki Nishio,Masaru Komatsu,Naohiro Shibata,Kouichi Shimakawa,Noriyuki Sueyoshi,Toshiro Ura,Kaori Satoh,Masahiro Toyokawa,Tatsuya Nakamura,Yasunao Wada,Tamaki Orita,Tomomi Kofuku,Katsutoshi Yamasaki,Masako Sakamoto,Shohiro Kinoshita,Masanori Aihara,Yoshichika Arakawa +16 more
TL;DR: Many species of MBL-positive gram-negative rods are distributed widely in different hospitals in the Kinki region of Japan, suggesting the nosocomial spread of the organism in each hospital.
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Increase of the USA300 clone among community-acquired methicillin- susceptible Staphylococcus aureus causing invasive infections
Michelle L. McCaskill,Edward O. Mason,Sheldon L. Kaplan,Wendy A. Hammerman,Wendy A. Hammerman,Linda B. Lamberth,Kristina G. Hulten,Kristina G. Hulten +7 more
TL;DR: USA300 accounted for a growing proportion of CA-MSSA isolates among children and was associated with increased numbers of invasive CA- MSSA infections at TCH, especially osteomyelitis.
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Appraising contemporary strategies to combat multidrug resistant gram-negative bacterial infections--proceedings and data from the Gram-Negative Resistance Summit.
Marin H. Kollef,Yoav Golan,Scott T. Micek,Andrew F. Shorr,Andrew F. Shorr,Marcos I. Restrepo,Marcos I. Restrepo +6 more
TL;DR: The Gram-Negative Resistance Summit convened national opinion leaders for the purpose of analyzing current literature, epidemiologic trends, clinical trial data, therapeutic options, and treatment guidelines related to the management of antibiotic-resistant GNB infections.
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Plasmid-Mediated Carbapenem-Hydrolyzing β-Lactamase KPC-2 in Klebsiella pneumoniae Isolate from Greece
TL;DR: A K. pneumoniae isolate from Greece that produced β-lactamase KPC-2 is reported, which was resistant to all antibiotics except gentamicin according to disk diffusion susceptibility testing results and showed significant carbapenem hydrolyzing activity.
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Drug resistance in Campylobacter jejuni, C coli, and C lari isolated from humans in north west England and Wales, 1997.
R T Thwaites,J A Frost +1 more
TL;DR: Resistance to quinolones in campylobacters from human infection may relate to clinical overuse or use of fluoroquinolone drugs in animal husbandry, and veterinary and clinical use should be reconsidered.