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Open AccessJournal ArticleDOI

Permanent dipole moment of tRNA's and variation of their structure in solution.

Dietmar Porschke, +1 more
- 01 Aug 1990 - 
- Vol. 58, Iss: 2, pp 403-411
TLDR
The structure of six different tRNA molecules has been analyzed in solution by electrooptical measurements and by bead model simulations and these measurements indicate that the structure of some other tRNA's in solution is different, even in cases with the same number of nucleotide residues.
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This article is published in Biophysical Journal.The article was published on 1990-08-01 and is currently open access. It has received 16 citations till now. The article focuses on the topics: Native state.

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Citations
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Journal ArticleDOI

Dielectrophoretic manipulation of ribosomal RNA.

TL;DR: These results are the first demonstration of DEP for fast capture and release of rRNA units, opening new opportunities for rRNA-based biosensing devices.
Journal ArticleDOI

Time-Resolved Analysis of Macromolecular Structures During Reactions by Stopped-Flow Electrooptics

TL;DR: A stopped-flow field-jump instrument and its use for the analysis of macromolecular structure changes during reactions is described, which indicates that all the reaction states found in the present investigation are complexes with insertion of ethidium residues between basepairs.
Journal ArticleDOI

Global Structure and Flexibility of Hairpin Ribozymes with Extended Terminal Helices

TL;DR: The observation of two relaxation processes for the hairpin constructs at high field strengths indicates stretching to a more elongated state; the fast process with a time constant of the order of 50 ns is assigned to reversion of stretching, the slow process to overall rotation.
Journal ArticleDOI

Brownian dynamics simulation of electrooptical transients for solutions of rigid macromolecules

TL;DR: In this article, the authors describe computer programs for the simulation of electrooptical transients without restrictions on molecular parameters or electric field strengths, which are consistent with analytical results, valid, e.g., for the limit of zero field strength, but have been extended to ranges, where analytical results are not available.
Journal ArticleDOI

Prediction of solution properties and dynamics of RNAs by means of Brownian dynamics simulation of coarse-grained models: Ribosomal 5S RNA and phenylalanine transfer RNA

TL;DR: A computational scheme for predicting global properties and mimicking the internal dynamics of RNA molecules in solution is presented and indicates that the model is able to capture the tertiary structure of RNA in solution.
References
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Journal ArticleDOI

Threshold effects observed in conformation changes induced by electric fields.

TL;DR: In this paper, it was demonstrated that the single-strand helix-coil transition in poly(A, poly(dA), and poly(C) can be induced by application of high electric fields.
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