Philadelphia Panel Evidence-Based Clinical Practice Guidelines on Selected Rehabilitation Interventions: Overview and Methodology
John Albright,Richard Allman,Richard Paul Bonfiglio,Alicia Conill,Bruce H. Dobkin,Andrew A. Guccione,Scott Hasson,Randolph Russo,Paul G. Shekelle,Jeffrey L Susman,George A. Wells,Peter Tugwell,Lucie Brosseau,Vivian Robinson,Vivian Robinson,Ian D. Graham,Ian D. Graham,Beverley Shea,Beverley Shea,Jessie McGowan +19 more
TLDR
This methodology of developing EBCPGs provides a structured approach to assessing the literature and developing E BCPGs that incorporates clinicians' feedback and is widely acceptable to practicing clinicians.Abstract:
Introduction. A structured and rigorous methodology was developed for the formulation of evidence-based clinical practice guidelines (EBCPGs), then was used to develop EBCPGs for selected rehabilitation interventions for the management of low back, neck, knee, and shoulder pain. Methods. Evidence from randomized controlled trials (RCTs) and observational studies was identified and synthesized using methods defined by the Cochrane Collaboration that minimize bias by using a systematic approach to literature search, study selection, data extraction, and data synthesis. Meta-analyses were conducted where possible. The strength of evidence was graded as level I for RCTs or level II for nonrandomized studies. Developing Recommendations. An expert panel was formed by inviting stakeholder professional organizations to nominate a representative. This panel developed a set of criteria for grading the strength of both the evidence and the recommendation. The panel decided that evidence of clinically important benefit (defined as 15% greater relative to a control based on panel expertise and empiric results) in patient-important outcomes was required for a recommendation. Statistical significance was also required but was insufficient alone. Patient-important outcomes were decided by consensus as being pain, function, patient global assessment, quality of life, and return to work, providing that these outcomes were assessed with a scale for which measurement reliability and validity have been established. Validating the Recommendations. A feedback survey questionnaire was sent to 324 practitioners from 6 professional organizations. The response rate was 51%. Results. Eight positive recommendations of clinical benefit were developed. These recommendations were mainly in agreement with previous EBCPGs, although some were not covered by other EBCPGs. There was wide agreement with these recommendations from practitioners (greater than 75% agreement). For several interventions and indications (eg, thermotherapy, therapeutic ultrasound, massage, electrical stimulation, mechanical traction), there was a lack of evidence regarding efficacy. Conclusions. This methodology of developing EBCPGs provides a structured approach to assessing the literature and developing EBCPGs that incorporates clinicians' feedback and is widely acceptable to practicing clinicians. Further well-designed RCTs are warranted regarding the use of several interventions where evidence was insufficient to make recommendations.read more
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Hydrotherapy Versus Conventional Land-Based Exercise for the Management of Patients With Osteoarthritis of the Knee: A Randomized Clinical Trial
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Resistance exercise training for fibromyalgia.
Angela J Busch,Sandra C. Webber,Rachel S Richards,Julia Bidonde,Candice L Schachter,Laurel A Schafer,Adrienne Danyliw,Anuradha Sawant,Vanina Dal Bello-Haas,Tamara Rader,Tom J. Overend +10 more
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Shoulder injuries in the throwing athlete.
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