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Potential anti-diabetic properties of Merlot grape pomace extract: An in vitro, in silico and in vivo study of α-amylase and α-glucosidase inhibition.

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TLDR
The results suggest that the MGPE can be adequate for maintaining normal blood levels after food ingestion, and indicates that several phenolic substances were the most likely polyphenols responsible for the α-amylase inhibition caused by MGPE.
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This article is published in Food Research International.The article was published on 2020-11-01 and is currently open access. It has received 34 citations till now. The article focuses on the topics: Pomace & Amylase.

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Current trends and possibilities for exploitation of Grape pomace as a potential source for value addition.

TL;DR: In this article, the authors present a review on value-added by-products that are used for societal benefits concerning the potential for human health and a sustainable environment, and summarize the existing information/knowledge on several green technologies for the recovery of value added byproducts.
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Understanding phenolic acids inhibition of α-amylase and α-glucosidase and influence of reaction conditions.

TL;DR: In this article, the authors presented the results of the Spanish Ministry of Science and Innovation (Project RTI 2018-095919-B-C21, Project RTI2018-09 5919-C-C 21, Project RTE2018 B-C22) and the European Regional Development Fund (FEDER) and Generalitat Valenciana (Project Prometeo 2017/189).
Journal ArticleDOI

Understanding phenolic acids inhibition of α-amylase and α-glucosidase and influence of reaction conditions

- 01 Mar 2022 - 
TL;DR: In this article , the potential inhibition of nine phenolic acids against α-amylase and α-glucosidase was studied applying different methodologies to understand interactions between phenolic acid and either enzymes or substrates.
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Influence of the extraction method on the recovery of bioactive phenolic compounds from food industry by-products

TL;DR: In this article , the authors provide an update on advanced technologies for the sustainable and efficient recovery of phenolics from plant matrices, including the composition and polarity of the extractant, the optimal sample particle size and sample:solvent ratio, as well as pH, pressure and temperature.
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Exploring the plant-derived bioactive substances as antidiabetic agent: An extensive review.

TL;DR: In this paper , a review focusing on antidiabetic plants, along with their bioactive constituent, chemically characterization, and plant-based diets for diabetes management is presented, which provides researchers with data that may be used to build future strategies, such as identifying promising bioactive molecules to make diabetes management easier.
References
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Journal ArticleDOI

A new look at the statistical model identification

TL;DR: In this article, a new estimate minimum information theoretical criterion estimate (MAICE) is introduced for the purpose of statistical identification, which is free from the ambiguities inherent in the application of conventional hypothesis testing procedure.
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Features and development of Coot.

TL;DR: Coot is a molecular-graphics program designed to assist in the building of protein and other macromolecular models and the current state of development and available features are presented.
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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

TL;DR: AutoDock4 incorporates limited flexibility in the receptor and its utility in analysis of covalently bound ligands is reported, using both a grid‐based docking method and a modification of the flexible sidechain technique.
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Development and validation of a genetic algorithm for flexible docking.

TL;DR: GOLD (Genetic Optimisation for Ligand Docking) is an automated ligand docking program that uses a genetic algorithm to explore the full range of ligand conformational flexibility with partial flexibility of the protein, and satisfies the fundamental requirement that the ligand must displace loosely bound water on binding.
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