Journal ArticleDOI
Potentiometric pKa determination of standard substances in binary solvent systems
Roman Wróbel,Lech Chmurzyński +1 more
Reads0
Chats0
TLDR
In this paper, a new method was developed for the determination in binary solvent systems of acid dissociation constants of compounds (molecular acids or phenols) used as p K a standards in potentiometric measurements.About:
This article is published in Analytica Chimica Acta.The article was published on 2000-01-24. It has received 49 citations till now. The article focuses on the topics: Binary system & Determination of equilibrium constants.read more
Citations
More filters
Journal ArticleDOI
Determination of pKa values of active pharmaceutical ingredients
TL;DR: A critical review of published methods and approaches for the determination of acid dissociation constants, with a special emphasis on the p K a values of active pharmaceutical ingredients, can be found in this article.
Journal ArticleDOI
Determination of pKa values of some hydroxylated benzoic acids in methanol–water binary mixtures by LC methodology and potentiometry
TL;DR: The data obtained have been used to test the feasibility of an estimation of dissociation constants in a methanol-water medium from the relationship between pK(a) values and the organic cosolvent fraction in the mixtures.
Journal ArticleDOI
Capillary zone electrophoresis in non-aqueous solutions: pH of the background electrolyte.
Simo P. Porras,Ernst Kenndler +1 more
TL;DR: The relevant aspects when dealing with primary standard (PS) and secondary standard (SS) as recommended by the International Union of Pure and Applied Chemistry (IUPAC), and the usage of the operational pH are discussed with special emphasis to non-aqueous solvents.
Journal ArticleDOI
Upper Rim Guanidinocalix[4]arenes as Artificial Phosphodiesterases
Laura Baldini,Roberta Cacciapaglia,Alessandro Casnati,Luigi Mandolini,Riccardo Salvio,Francesco Sansone,Rocco Ungaro +6 more
TL;DR: Calix[4]arene derivatives, blocked in the cone conformation and functionalized with two to four guanidinium units at the upper rim were synthesized and investigated as catalysts in the cleavage of the RNA model compound 2-hydroxypropyl p-nitrophenyl phosphate, pointing to a high level of cooperation between catalytic groups.
Journal ArticleDOI
A critical overview of non-aqueous capillary electrophoresis. Part I: mobility and separation selectivity.
TL;DR: This two-part review critically gives an overview on the theoretical and practical advances in non-aqueous capillary electrophoresis (NACE) achieved over the recent five years and discusses - critically - examples from the literature with particular interest to the topic.
References
More filters
Journal ArticleDOI
Dissociation constants of uncharged and monovalent cation acids in dimethyl sulfoxide
Journal ArticleDOI
Calibration of the Glass Electrode in Acetonitrile. Shape of Potentiometric Titration Curves. Dissociation Constant of Picric Acid1
I. M. Kolthoff,M. K. Chantooni +1 more
Journal ArticleDOI
A general method for the determination of the stoichiometry of unknown species in multicomponent systems from physicochemical measurements
Jaroslaw Kostrowicki,Adam Liwo +1 more
TL;DR: Problems of determinability of an equilibrium model, of deciding on the most probable model, and of estimating the number of species present are discussed.
Journal ArticleDOI
Determination of equilibrium parameters by minimization of an extended sum of squares.
Jaroslaw Kostrowicki,Adam Liwo +1 more
TL;DR: A method is proposed for the evaluation of equilibrium parameters from potentiometric data, in which all the sources of random error are taken into account and the residuals in all the quantities subject to error are included in the minimized sum.