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Precision polysaccharide synthesis catalyzed by enzymes.

Jun-ichi Kadokawa
- 14 Feb 2011 - 
- Vol. 111, Iss: 7, pp 4308-4345
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This article is published in Chemical Reviews.The article was published on 2011-02-14. It has received 189 citations till now.

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Enzymes as Green Catalysts for Precision Macromolecular Synthesis

TL;DR: The enzymatic polymerizations allowed the first in vitro synthesis of natural polysaccharides having complicated structures like cellulose, amylose, xylan, chitin, hyaluronan, and chondroitin, and producing minimal byproducts.
Journal ArticleDOI

Chitin Whiskers: An Overview

TL;DR: The research and development of CHW related areas are much slower than those of CW, however, CHWs are still of strategic importance in the resource scarcity periods because of their abundant availability and special properties.
Journal ArticleDOI

Encapsulation of active ingredients in polysaccharide-protein complex coacervates.

TL;DR: This review discusses on the overview of polysaccharide-protein complex coacervates and their use for the encapsulation of diverse active ingredients, designing and controlling of the capsules for delivery systems and developments in the area.
Journal ArticleDOI

Enzymatic methods for glyco(diversification/randomization) of drugs and small molecules.

TL;DR: This review covers the influence of Glycosylation upon various drug properties, the classes of glycosyl-conjugating enzymes amenable to glyco(randomization/diversification) schemes, approaches to the synthesis of required substrates and specific examples of glycorandomized libraries utilizing both wild-type and engineered enzymes.
Journal ArticleDOI

Bioproduction of chitooligosaccharides: present and perspectives.

TL;DR: Other emerging technologies such as direct degradation of chitin from crustacean shells and microbial cell walls, enzymatic synthesis of COS from small building blocks, and protein engineering technology for chit in-related enzymes have been discussed as the most significant challenge for industrial application.
References
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Journal ArticleDOI

Cellulose: Fascinating Biopolymer and Sustainable Raw Material

TL;DR: The current knowledge in the structure and chemistry of cellulose, and in the development of innovative cellulose esters and ethers for coatings, films, membranes, building materials, drilling techniques, pharmaceuticals, and foodstuffs are assembled.
Journal ArticleDOI

Functions of Cell Surface Heparan Sulfate Proteoglycans

TL;DR: Current analyses of genetic defects in Drosophila melanogaster, mice, and humans confirm most of these activities in vivo and identify additional processes that involve cell surface heparan sulfate proteoglycans.
Journal ArticleDOI

Chitosan chemistry and pharmaceutical perspectives.

TL;DR: Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. S. Nagar, Punjab-160 062, India, Institute of Biochemistry, Faculty of Medicine, Polytechnic University, Via Ranieri 67, IT-60100 Ancona, Italy, and Department of Medicinal Chemistry & Natural Products,The Hebrew University of Jerusalem, School of Pharmacy-Faculty of medicine, Jerusalem 91120, Israel.
Journal ArticleDOI

Structures and mechanisms of glycosyl hydrolases

TL;DR: The wealth of information provided by the recent structure determinations of many different glycosyl hydrolases shows that the substrate specificity and the mode of action of these enzymes are governed by exquisite details of their three-dimensional structures rather than by their global fold.
Journal ArticleDOI

Einfluss der Configuration auf die Wirkung der Enzyme

TL;DR: In this article, the Spaltung der Glucoside durch die Enzyme der Hefe and das Emulsin in hohem Grade von der Konfiguration des Molekuls abhangig is discussed.
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