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Journal ArticleDOI

Prediction of pulmonary embolism in the emergency department: the revised Geneva score.

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TLDR
A new prediction rule is derived that is entirely based on clinical variables and is independent of physicians' implicit judgment by using a large multicenter cohort of patients admitted to the emergency department for clinically suspected pulmonary embolism.
Abstract
To improve diagnosis of pulmonary embolism (PE), the authors constructed a simple scoring system to estimate the probability of PE. Clinical predictors included age, previous venous thromboembolism...

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Citations
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Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration.

TL;DR: In virtually all medical domains, diagnostic and prognostic multivariable prediction models are being developed, validated, updated, and implemented with the aim to assist doctors and individuals in estimating probabilities and potentially influence their decision making.
Journal ArticleDOI

2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism

TL;DR: Guidelines summarize and evaluate all available evidence at the time of the writing process, on a particular issue with the aim of assisting health professionals in selecting the best management strategies for an individual patient, with a given condition, taking into account the impact on outcome.
References
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Journal ArticleDOI

Prediction of Creatinine Clearance from Serum Creatinine

Donald W. Cockcroft, +1 more
- 01 Jan 1976 - 
TL;DR: A formula has been developed to predict Creatinine clearance from serum creatinine (Scr) in adult males: Ccr = (140 – age) (wt kg)/72 × Scr (mg/100ml) (15% less i).
Journal ArticleDOI

Value of the ventilation/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED).

Pioped Investigators
- 23 May 1990 - 
TL;DR: Follow-up and angiography together suggest pulmonary embolism occurred among 12% of patients with low-probability scans, and clinical assessment combined with the ventilation/perfusion scan established the diagnosis or exclusion of pulmonary emblism only for a minority of patients--those with clear and concordant clinical and ventilation-perfusions scan findings.
Journal ArticleDOI

Derivation of a Simple Clinical Model to Categorize Patients Probability of Pulmonary Embolism: Increasing the Models Utility with the SimpliRED D-dimer

TL;DR: The combination of a score < or =4.0 by the authors' simple clinical prediction rule and a negative SimpliRED D-Dimer result may safely exclude PE in a large proportion of patients with suspected PE.
Journal ArticleDOI

Clinical prediction rules. Applications and methodological standards.

TL;DR: Qualitative standards that can be used to decide whether a prediction rule is suitable for adoption in a clinician's practice are described and applied to 33 reports of prediction rules.
Journal ArticleDOI

Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer.

TL;DR: A diagnostic algorithm based on a simple model and a non-enzyme-linked immunosorbent d-dimer assay was used in patients presenting to emergency departments with suspected pulmonary embolism to demonstrate the safety of excluding the diagnosis of pulmonary emblism in an emergency department using diagnostic algorithms based on pretest probability and d-Dimer assay results.
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