Journal ArticleDOI
Prediction of pulmonary embolism in the emergency department: the revised Geneva score.
Grégoire Le Gal,Marc Philip Righini,Pierre-Marie Roy,Olivier Sanchez,Drahomir Aujesky,Henri Bounameaux,Arnaud Perrier +6 more
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TLDR
A new prediction rule is derived that is entirely based on clinical variables and is independent of physicians' implicit judgment by using a large multicenter cohort of patients admitted to the emergency department for clinically suspected pulmonary embolism.Abstract:
To improve diagnosis of pulmonary embolism (PE), the authors constructed a simple scoring system to estimate the probability of PE. Clinical predictors included age, previous venous thromboembolism...read more
Citations
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Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Clive Kearon,Elie A. Akl,Anthony J. Comerota,Paolo Prandoni,Henri Bounameaux,Samuel Z. Goldhaber,Michael E. Nelson,Philip S. Wells,Michael K. Gould,Francesco Dentali,Mark Crowther,Susan R. Kahn +11 more
TL;DR: Strong recommendations apply to most patients, whereas weak recommendations are sensitive to differences among patients, including their preferences.
Journal ArticleDOI
Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report
Clive Kearon,Elie A. Akl,Elie A. Akl,Joseph Ornelas,Allen J. Blaivas,David Jiménez,Henri Bounameaux,Menno V. Huisman,Christopher S. King,Timothy A. Morris,Namita Sood,Scott M. Stevens,Janine R.E. Vintch,Philip S. Wells,Scott C. Woller,Lisa K. Moores +15 more
TL;DR: Recommendations on 12 topics that were in the 9th edition of these guidelines are updated, and 3 new topics are addressed.
Journal ArticleDOI
Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration.
Karel G.M. Moons,Douglas G. Altman,Johannes B. Reitsma,John P. A. Ioannidis,Petra Macaskill,Ewout W. Steyerberg,Andrew J. Vickers,David F. Ransohoff,Gary S. Collins +8 more
TL;DR: In virtually all medical domains, diagnostic and prognostic multivariable prediction models are being developed, validated, updated, and implemented with the aim to assist doctors and individuals in estimating probabilities and potentially influence their decision making.
Journal ArticleDOI
Guidelines on the Diagnosis and Management of Acute Pulmonary Embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)
Adam Torbicki,Arnaud Perrier,Stavros Konstantinides,Giancarlo Agnelli,Nazzareno Galiè,Piotr Pruszczyk,Frank M. Bengel,Adrian J B Brady,Daniel Ferreira,Uwe Janssens,Walter Klepetko,Eckhard Mayer,Martine Remy-Jardin,Jean-Pierre Bassand,Alec Vahanian,John Camm,Raffaele De Caterina,Veronica Dean,Kenneth Dickstein,Gerasimos Filippatos,Christian Funck-Brentano,Irene Hellemans,Steen Dalby Kristensen,Keith McGregor,Udo Sechtem,Sigmund Silber,Michal Tendera,Petr Widimsky,José Luis Zamorano,José Luis Zamorano,Felicita Andreotti,Michael Ascherman,George Athanassopoulos,Johan De Sutter,David Fitzmaurice,Tamás Forster,Magda Heras,Guillaume Jondeau,Keld Kjeldsen,Juhani Knuuti,Irene Lang,Mattie J. Lenzen,Jose Lopez-Sendon,Petros Nihoyannopoulos,Leopoldo Pérez de Isla,Udo Schwehr,Lucia Torraca,Jean-Luc Vachiery +47 more
TL;DR: Non-thrombotic PE does not represent a distinct clinical syndrome but may be due to a variety of embolic materials and result in a wide spectrum of clinical presentations, making the diagnosis difficult.
Journal ArticleDOI
2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism
Stavros Konstantinides,Adam Torbicki,David Fitzmaurice,Simón J,R. Gibbs,Menno V. Huisman,Marc Humbert,John Lekakis,Nicolas Meneveau,Lars Hvilsted Rasmussen,Thomas H. Schindler,Anton Vonk Noordegraaf,José Luis Zamorano,Maurizio Zompatori +13 more
TL;DR: Guidelines summarize and evaluate all available evidence at the time of the writing process, on a particular issue with the aim of assisting health professionals in selecting the best management strategies for an individual patient, with a given condition, taking into account the impact on outcome.
References
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Journal ArticleDOI
Prediction of Creatinine Clearance from Serum Creatinine
Donald W. Cockcroft,M H Gault +1 more
TL;DR: A formula has been developed to predict Creatinine clearance from serum creatinine (Scr) in adult males: Ccr = (140 – age) (wt kg)/72 × Scr (mg/100ml) (15% less i).
Journal ArticleDOI
Value of the ventilation/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED).
TL;DR: Follow-up and angiography together suggest pulmonary embolism occurred among 12% of patients with low-probability scans, and clinical assessment combined with the ventilation/perfusion scan established the diagnosis or exclusion of pulmonary emblism only for a minority of patients--those with clear and concordant clinical and ventilation-perfusions scan findings.
Journal ArticleDOI
Derivation of a Simple Clinical Model to Categorize Patients Probability of Pulmonary Embolism: Increasing the Models Utility with the SimpliRED D-dimer
Philip S. Wells,David Anderson,Marc A. Rodger,Jeffrey S. Ginsberg,Clive Kearon,Michael Gent,Alexander G.G. Turpie,Janis Bormanis,Jeffrey I. Weitz,Michael Chamberlain,Dennis Bowie,David Barnes,Jack Hirsh +12 more
TL;DR: The combination of a score < or =4.0 by the authors' simple clinical prediction rule and a negative SimpliRED D-Dimer result may safely exclude PE in a large proportion of patients with suspected PE.
Journal ArticleDOI
Clinical prediction rules. Applications and methodological standards.
TL;DR: Qualitative standards that can be used to decide whether a prediction rule is suitable for adoption in a clinician's practice are described and applied to 33 reports of prediction rules.
Journal ArticleDOI
Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer.
Philip S. Wells,David Anderson,Marc A. Rodger,Ian G. Stiell,Jonathan Dreyer,David Barnes,Melissa A. Forgie,George Kovacs,John W. Ward,Michael J. Kovacs +9 more
TL;DR: A diagnostic algorithm based on a simple model and a non-enzyme-linked immunosorbent d-dimer assay was used in patients presenting to emergency departments with suspected pulmonary embolism to demonstrate the safety of excluding the diagnosis of pulmonary emblism in an emergency department using diagnostic algorithms based on pretest probability and d-Dimer assay results.
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