Prevalence and Course of IgA and IgG Antibodies against SARS-CoV-2 in Healthcare Workers during the First Wave of the COVID-19 Outbreak in Germany: Interim Results from an Ongoing Observational Cohort Study
Mark Reinwald,Peter Markus Deckert,Oliver Ritter,Henrike Andresen,Andreas G. Schreyer,Karsten Henrich Weylandt,Werner Dammermann,Stefan Lüth +7 more
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In this paper, the prevalence of antibodies against SARS-CoV-2 in HCWs at baseline and follow up with regard to clinical signs and symptoms in two university hospitals in Brandenburg, Germany.About:
This article is published in Healthcare.The article was published on 2021-04-22 and is currently open access. It has received 3 citations till now. The article focuses on the topics: Seroprevalence.read more
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The German Translation of the Stress and Anxiety to Viral Epidemics-9 (SAVE-9) Scale: Results from Healthcare Workers during the Second Wave of COVID-19
Julia König,Seockhoon Chung,Verena Ertl,Bettina K. Doering,Hannah Comtesse,Johanna Unterhitzenberger,Antonia Barke +6 more
TL;DR: In this paper, the authors report on data collected from 484 German HCW between November 2020 and March 2021, during the "second wave" of coronavirus infections, and find significant differences between groups of HCW on the SAVE-9 which were consistent with the literature but did not appear on the other mental health measures.
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Seroprevalence of SARS-CoV-2 Antibodies in Employees of Three Hospitals of a Secondary Care Hospital Network in Germany and an Associated Fire Brigade: Results of a Repeated Cross-Sectional Surveillance Study Over 1 Year
Anke Hildebrandt,Oktay Hökelekli,Lutz Uflacker,Henrik Rudolf,Michael Paulussen,Sören Gatermann +5 more
TL;DR: Investigating how infection spreads within three local hospitals and an associated fire brigade in Germany by testing employees for the presence of SARS-CoV-2 IgG antibodies over one year found HCWs presumably had an additional occupational risk for infection in the second and third wave due to an increase of infection pressure with more COVID-19 patients treated.
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Elevated serum IgA following vaccination against SARS-CoV-2 in a cohort of high-risk first responders
Brian T. Montague,Matthew F. Wipperman,Erica Chio,Rowena Crow,Andrea T. Hooper,Meagan P. O'Brien,Eric A. F. Simões +6 more
TL;DR: In this article , the authors evaluated the serum anti-spike (anti-S) IgG, anti-nucleocapsid (antiN) and anti-S IgA response following vaccination against SARS-CoV-2 in a cohort of first-responders.
References
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Comparison of six commercially available SARS-CoV-2 antibody assays-Choice of assay depends on intended use.
Anna Christine Nilsson,Dorte Kinggaard Holm,Ulrik Stenz Justesen,Thøger Gorm-Jensen,Nanna Skaarup Andersen,Anne Øvrehus,Isik Somuncu Johansen,Jens Michelsen,Ulrik Sprogøe,Søren Thue Lillevang +9 more
TL;DR: The sensitive and semi-quantitative ELISA assays are most appropriate for serologic detection of SARS-CoV-2 infection in mild cases and Livzon LFT and Euroimmun ELISA had the highest specificity among the IgG assays, making them most suitable for seroprevalence studies.
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Factors associated with asymptomatic infection in health-care workers with severe acute respiratory syndrome coronavirus 2 infection in Wuhan, China: a multicentre retrospective cohort study.
Shuai Zhang,Mengfei Guo,Feng Wu,Nian Xiong,Yanling Ma,Zhihui Wang,Limin Duan,Lan Chen,Haixia Ouyang,Yang Jin +9 more
TL;DR: Those who have performed tracheal intubation or extubation were most likely to develop related symptoms, while those taking aggressive measures including consistent use of N95 masks, and eye protection tended to be asymptomatic cases.
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Comparison of Five Serological Assays for the Detection of SARS-CoV-2 Antibodies.
Anja Dörschug,Julian Schwanbeck,Andreas Hahn,Anke Hillebrecht,Sabine Blaschke,Kemal Mese,Uwe Groß,Sascha Dierks,Hagen Frickmann,Andreas E. Zautner +9 more
TL;DR: In this paper, the authors compared five commercially available diagnostic assays for the diagnostic identification of SARS-CoV-2-specific antibodies, with the best results being found for immunoglobulin G.
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Comparative analysis of three laboratory based serological assays for SARS-CoV-2 in an Australian cohort.
Natalie Davidson,Jenny Evans,D. Giammichele,H. Powell,P. Hobson,B. Teis,H. Glover,K. B. Guppy-Coles,Jenny Robson +8 more
TL;DR: The EUROIMMUN Anti-SARS-CoV-2 IgA lacked specificity for acute diagnosis and all IgM assays offered poor diagnostic utility, and this assay would not be satisfactory for seroprevalence studies in the general Australian population given this is likely to be currently <1%.
Journal ArticleDOI
Making sense of a negative COVID-19 swab test
TL;DR: The findings suggest that testing of specimens from multiple sites or obtaining lower respiratory tract samples may improve the sensitivity and reduce false-negative test results, and the utility of chest computed tomography imaging in screening patients in whom COVID-19 is clinically suspected.