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Showing papers in "Journal of Hospital Infection in 2021"


Journal ArticleDOI
TL;DR: Intention to get vaccinated against COVID-19 reached 75% in HCWs with discrepancies between occupational categories, and CO VID-19 pandemic had no positive effect on flu vaccine acceptance rate.

421 citations


Journal ArticleDOI
TL;DR: Seroprevalence of SARS-CoV-2 antibodies among HCWs is high and the following factors were associated with seropositivity: male gender, Black, Asian, and Hispanic HCWs, work in a coronavirus disease 2019 unit, patient-related work, frontline health care workers, health care assistants, personal protective equipment shortage, and household contact with suspected or confirmed COVID-19 patients.

243 citations




Journal ArticleDOI
TL;DR: In this article, a literature search was performed through Pubmed and Web of Science databases for articles published up to 20th March 2021 to discuss the incidence, characteristics, diagnostic criteria, biomarkers, and outcomes of hospitalized patients diagnosed with CAPA.

90 citations


Journal ArticleDOI
TL;DR: The presence of low or undetectable concentrations of viral RNA in the air supports current guidance on the use of specific personal protective equipment for aerosol-generating and non-aerosol-Generating procedures.

87 citations


Journal ArticleDOI
TL;DR: Modification to current working practices is urgently required to improve HCWs’ resilience to wearing PPE during pandemics.

74 citations


Journal ArticleDOI
TL;DR: In this article, the authors analyzed the impact of coinfections on the outcome of hospitalized COVID-19 patients and found that coinfected patients stayed hospitalized longer and had an increased odds of dying (odds ratio (OR): 13.45; R2 ǫ = 0.31).

70 citations


Journal ArticleDOI
TL;DR: It is concluded that Quat disinfectants rapidly inactivate SARS-CoV-2, making them potentially useful for controlling Sars-Cov-2 spread in hospitals and the community.

57 citations


Journal ArticleDOI
TL;DR: In this article, the effectiveness of a guideline implemented at Sheffield Teaching Hospitals NHS Foundation Trust that recommends withholding antibiotics in patients with low serum procalcitonin (PCT), defined as ≤ 0.25 ng/mL, was evaluated.

49 citations



Journal ArticleDOI
TL;DR: In this paper, a comprehensive systematic review provides an up-to-date compilation of clinical trials, reported between 2014 and 2020, assessing hand hygiene interventions in order to inform healthcare leaders and practitioners regarding approaches to reduce healthcareassociated infections using hand hygiene.

Journal ArticleDOI
TL;DR: In this article, the authors used an automated hand hygiene recording system to measure HCW hand hygiene on entry to and exit from patient rooms throughout the COVID-19 pandemic.


Journal ArticleDOI
TL;DR: In this paper, the authors investigated the sources of infection among healthcare workers (HCWs) and patients in a teaching hospital during the early stages of the COVID-19 pandemic with epidemiological and whole genome sequencing data.

Journal ArticleDOI
TL;DR: EtOH, IPA, and SH at multiple concentrations efficiently inactivated infectious virus on hard surfaces, typical of those found in public places.

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the clinical characteristics and risk factors for the isolation of multi-drug-resistant (MDR) Gram-negative bacteria (GNB) from critically ill COVID-19 patients.

Journal ArticleDOI
TL;DR: In this article, the authors evaluated the available evidence testing the in-vitro and invivo effects of oral antiseptics to inactivate or eradicate coronaviruses.

Journal ArticleDOI
TL;DR: Most countries have IPC programme and guidelines, but many less have invested adequate resources and translated them in implementation and monitoring, particularly in low-income countries, according to the World Health Organization IPC core components.

Journal ArticleDOI
TL;DR: In this article, the authors conducted a systematic review following PRISMA guidelines, searching Medline, Embase and the Cochrane Library, and the main clinical trials' registries (WHO ICTRP, ClinicalTrials.gov, Cochrane and EU Clinical Trial Register).


Journal ArticleDOI
TL;DR: Commercial available antiseptic mouthwashes based on the actives chlorhexidine digluconate and octenidine dihydrochloride were investigated regarding their efficacy against SARS-CoV-2 using the European Standard 14476 and the OCT-mouthwash constituted an interesting candidate for future clinical studies to prove its effectiveness.

Journal ArticleDOI
TL;DR: In this article, the authors investigated a SARS-CoV-2 outbreak in a university-affiliated rehabilitation clinic and found that healthcare workers played an essential role in cross-transmission, with a significantly higher fraction of infections (P 5; 82.3%) compared to other patients.

Journal ArticleDOI
TL;DR: In this article, the authors presented a one-year prospective incidence study of healthcare-associated infection (HAI) observed in one teaching hospital and one general hospital in NHS Scotland as part of the Evaluation of Cost of Nosocomial Infection (ECONI) study.

Journal ArticleDOI
TL;DR: In this paper, the authors highlight the efficacy of several disinfection methods against SARS-CoV-2, based on up-to-date evidence found in literature, and conduct a research through two databases to assess the disinfection techniques used against the virus.

Journal ArticleDOI
TL;DR: In this article, the authors examined the anti-SARS-CoV-2 activity of the potent disinfectant Cleverin, the major disinfecting component of which is chlorine dioxide (ClO2); and compared the results with that of sodium hypochlorite in the presence or absence of 0.5% or 1.0% foetal bovine serum (FBS).

Journal ArticleDOI
TL;DR: In this article, a prospective observational incidence study was undertaken for one year from April 2018 using data collected as part of the Evaluation of Cost of Nosocomial Infection (ECONI) study, using record linkage to national administrative data to provide full admission and discharge information.

Journal ArticleDOI
TL;DR: In this article, the authors used whole genome sequencing (WGS) of SARS-CoV-2 with contact tracing data to determine whether clusters of suspected intra-hospital SARS CoV2 transmission could be resolved.

Journal ArticleDOI
TL;DR: Novel nosocomial SARS-CoV-2 infection is not associated with increased mortality compared with community acquired infection and this was a prospective cohort study of all hospitalised patients in three acute hospitals with confirmed COVID-19.