Journal ArticleDOI
Promising cell-based therapy for bone regeneration using stem cells from deciduous teeth, dental pulp, and bone marrow.
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TLDR
It is demonstrated that stem cells from deciduous teeth, dental pulp, and bone marrow with PRP have the ability to form bone, andBone formation with DTSCs might have the potential to generate a graft between a child and parent.About:
This article is published in Cell Transplantation.The article was published on 2011-08-01. It has received 173 citations till now. The article focuses on the topics: Platelet-rich plasma & Bone regeneration.read more
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Stem cell-delivery therapeutics for periodontal tissue regeneration
TL;DR: This paper explores and analyses the stem cell types and cell delivery strategies that have been or have the potential to be used as therapeutics inperiodontal regenerative medicine, with particular emphasis placed on the efficacy and safety concerns of current stem cell-based periodontal therapies that may eventually enter into the clinic.
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Dental pulp stem cells: function, isolation and applications in regenerative medicine.
TL;DR: The ease of isolation of DPSCs from discarded or removed teeth offers a promising source of autologous cells, and their similarities with bone marrow stromal cells (BMSCs) suggest applications in musculoskeletal regenerative medicine.
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Clinical utility of stem cells for periodontal regeneration.
TL;DR: The aim of this review is to discuss the clinical utility of stem cells in periodontal regeneration by reviewing relevant literature that assesses theperiodontal-regenerative potential of stem Cells.
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Mesenchymal Stem Cells Derived from Dental Pulp: A Review
TL;DR: DPSCs are considered to have potential as stem cell source for orthopedic and oral maxillofacial reconstruction, and it has been suggested that they may have applications beyond the scope of the stomatognathic system.
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Human dental pulp stem cells: Applications in future regenerative medicine
TL;DR: This review will overview the information about isolation, cellular and molecular characterization and differentiation of DPSCs into various types of human cells and thus these cells have important applications in regenerative therapies for various diseases.
References
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Human Adipose Tissue Is a Source of Multipotent Stem Cells
Patricia A. Zuk,Min Zhu,Peter Ashjian,Daniel A. De Ugarte,Jerry I. Huang,Hiroshi Mizuno,Zeni Alfonso,John K. Fraser,Prosper Benhaim,Marc H. Hedrick +9 more
TL;DR: To confirm whether adipose tissue contains stem cells, the PLA population and multiple clonal isolates were analyzed using several molecular and biochemical approaches and PLA cells exhibited unique characteristics distinct from those seen in MSCs, including differences in CD marker profile and gene expression.
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Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo
TL;DR: Postnatal human DPSCs are isolated that have the ability to form a dentin/pulp-like complex and are compared with human bone marrow stromal cells, known precursors of osteoblasts.
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Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue.
TL;DR: Both UCB and AT are attractive alternatives to BM in isolating MSC: AT as it contains MSCs at the highest frequency and UCB as it seems to be expandable to higher numbers.
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SHED: Stem cells from human exfoliated deciduous teeth
Masako Miura,Stan Gronthos,Mingrui Zhao,Bai Lu,Larry W. Fisher,Pamela Gehron Robey,Songtao Shi +6 more
TL;DR: It is shown that a naturally exfoliated human organ contains a population of stem cells that are completely different from previously identified stem cells, which may be an unexpected unique resource for stem-cell therapies including autologous stem- cell transplantation and tissue engineering.
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Platelet-rich plasma: Growth factor enhancement for bone grafts
Robert E. Marx,Eric R. Carlson,Ralph M. Eichstaedt,Ralph M. Eichstaedt,Steven R Schimmele,Steven R Schimmele,James E. Strauss,Karen R. Georgeff +7 more
TL;DR: Monoclonal antibody assessment of cancellous cellular marrow grafts demonstrated cells that were capable of responding to the growth factors by bearing cell membrane receptors and evidenced a radiographic maturation rate 1.62 to 2.16 times that of grafts without platelet-rich plasma.