Protection of young children from influenza through universal vaccination
Reads0
Chats0
TLDR
Although future research could lead to an increase in the immunogenicity and potential efficacy of influenza vaccines, the available vaccines assure sufficient protection in most subjects aged ≥ 6 months, thus reducing the total burden of influenza in young children and justifying the recommendation for the universal vaccination of the whole pediatric population.Abstract:
Influenza is a very common disease among infants and young children, with a considerable clinical and socioeconomic impact. A significant number of health authorities presently recommend universal influenza vaccination for the pediatric population, but a large number of European health authorities is still reluctant to include influenza vaccination in their national vaccination programs. The reasons for this reluctance include the fact that the protection offered by the currently available vaccines is considered poor. This review shows that although future research could lead to an increase in the immunogenicity and potential efficacy of influenza vaccines, the available vaccines, even with their limits, assure sufficient protection in most subjects aged ≥ 6 months, thus reducing the total burden of influenza in young children and justifying the recommendation for the universal vaccination of the whole pediatric population. For younger subjects, the vaccination of their mother during pregnancy represents ...read more
Citations
More filters
Journal ArticleDOI
Maternal immunization: where are we now and how to move forward?
Ivo Vojtek,Ilse Dieussaert,T. Mark Doherty,Valentine Franck,Linda Hanssens,Jacqueline M. Miller,Rafik Bekkat-Berkani,Walid Kandeil,David Prado-Cohrs,Andrew Vyse +9 more
TL;DR: Years of experience suggest that maternal immunization against influenza, tetanus or pertussis has an acceptable safety profile, is well tolerated, effective and confers significant benefits to pregnant women and their infants.
Journal ArticleDOI
Global Perspectives on Immunization During Pregnancy and Priorities for Future Research and Development: An International Consensus Statement.
Bahaa Abu-Raya,Kirsten Maertens,Kathryn M. Edwards,Saad B. Omer,Janet A. Englund,Katie L. Flanagan,Katie L. Flanagan,Katie L. Flanagan,Matthew D. Snape,Gayatri Amirthalingam,Elke Leuridan,Pierre Van Damme,Vana Papaevangelou,Odile Launay,Ron Dagan,Magda Campins,Anna Franca Cavaliere,Tiziana Frusca,Sofia Guidi,Miguel O'Ryan,Ulrich Heininger,Tina Tan,Ahmed R. Alsuwaidi,Marco Aurélio Palazzi Sáfadi,Luz Maria Vilca,Nasamon Wanlapakorn,Shabir A. Madhi,Michelle L. Giles,Roman Prymula,Shamez N Ladhani,Federico Martinón-Torres,Litjen Tan,Lessandra Michelin,Giovanni Scambia,Nicola Principi,Susanna Esposito +35 more
TL;DR: A review of the current literature on immunization during pregnancy is provided and the gaps in knowledge are highlighted and a consensus of priorities for future research initiatives are highlighted in order to optimize protection for both the mother and the infant.
Journal ArticleDOI
Drugs for Influenza Treatment: Is There Significant News?
Nicola Principi,Barbara Camilloni,Anna Alunno,Ilaria Polinori,Alberto Argentiero,Susanna Esposito +5 more
TL;DR: The clinical roles of antiviral drugs against influenza that have been licensed in at least one country and the potential roles of compounds that are in development are shown.
Journal ArticleDOI
Prevention and Control of Influenza in Children
TL;DR: The aim is to provide real-time information about adverse events in children aged six months and up to 18 months to improve the quality of care and decrease the likelihood of adverse events and unnecessary hospital admissions.
Journal ArticleDOI
Influenza vaccination and prevention of antimicrobial resistance.
Susanna Esposito,Nicola Principi +1 more
TL;DR: Only when universal vaccination is accepted and implemented will the true advantages of the influenza vaccine in reducing AMR development be completely known and exploited.
References
More filters
Journal Article
Prevention and control of influenza : recommendations of the Advisory Committee on Immunization Practices (ACIP)
TL;DR: This report updates the 2000 recommendations by the Advisory Committee on Immunization Practices on the use of influenza vaccine and antiviral agents with new or updated information regarding the cost-effectiveness of influenza vaccination and the 2001-2002 trivalent vaccine virus strains.
Journal ArticleDOI
Vaccine Adjuvants: Putting Innate Immunity to Work
TL;DR: There remains a need for improved adjuvants that enhance protective antibody responses, especially in populations that respond poorly to current vaccines, and the larger challenge is to develop vaccines that generate strong T cell immunity with purified or recombinant vaccine antigens.
Journal ArticleDOI
The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children.
TL;DR: Healthy children younger than one year of age are hospitalized for illness attributable to influenza at rates similar to those for adults at high risk for influenza.
Journal ArticleDOI
Effectiveness of maternal influenza immunization in mothers and infants.
K. Zaman,Eliza Roy,Shams El Arifeen,Mahbubur Rahman,Rubhana Raqib,Emily Wilson,Saad B. Omer,Nigar S. Shahid,Robert F. Breiman,Mark C. Steinhoff +9 more
TL;DR: Inactivated influenza vaccine reduced proven influenza illness by 63% in infants up to 6 months of age and averted approximately a third of all febrile respiratory illnesses in mothers and young infants in Bangladesh.