Psychiatric manifestations of neurocysticercosis: a study of 38 patients from a neurology clinic in Brazil.
Orestes Vicente Forlenza,Antonio Helio Guerra Vieira Filho,J. P. S. Nobrega,L dos Ramos Machado,N G de Barros,C H de Camargo,M F da Silva +6 more
Reads0
Chats0
TLDR
Mild cognitive impairment may be a much more prevalent neuropsychological feature of patients with neurocysticercosis, and organic mechanisms related to brain lesions may underlie the mental changes.Abstract:
OBJECTIVE: To determine the frequency and features of psychiatric morbidity in a cross section of 38 outpatients with neurocysticercosis. METHODS: Diagnosis of neurocysticercosis was established by CT, MRI, and CSF analysis. Psychiatric diagnoses were made by using the present state examination and the schedule for affective disorders and schizophrenia-lifetime version; cognitive state was assessed by mini mental state examination and Strub and Black's mental status examination. RESULTS: Signs of psychiatric disease and cognitive decline were found in 65.8 and 87.5% of the cases respectively. Depression was the most frequent psychiatric diagnosis (52.6%) and 14.2% of the patients were psychotic. Active disease and intracranial hypertension were associated with higher psychiatric morbidity, and previous history of mood disorders was strongly related to current depression. Other variables, such as number and type of brain lesions, severity of neuropsychological deficits, epilepsy, and use of steroids did not correlate with mental disturbances in this sample. CONCLUSIONS: Psychiatric abnormalities, particularly depression syndromes, are frequent in patients with neurocysticercosis. Although regarded as a rare cause of dementia, mild cognitive impairment may be a much more prevalent neuropsychological feature of patients with neurocysticercosis. The extent to which organic mechanisms related to brain lesions may underlie the mental changes is yet unclear, although the similar sex distribution of patients with and without depression, as well as the above mentioned correlations, provide further evidence of the part played by organic factors in the cause of these syndromes.read more
Citations
More filters
Journal ArticleDOI
Neurocysticercosis: Updates on Epidemiology, Pathogenesis, Diagnosis, and Management
TL;DR: Patients with neurocysticercosis should be treated with corticosteroids, antiparasitic drugs, and shunting if hydrocephalus is present, and the pathogenesis and clinical manifestations vary with the site of infection and accompanying host response.
Journal ArticleDOI
Cysticercosis and epilepsy: a critical review.
TL;DR: There is a discrepancy between the results of serologic assays and neuroimaging studies: >50% of those individuals with NC diagnosed by computed tomography (CT) scan test EITB negative, and most seropositive individuals are asymptomatic.
Journal ArticleDOI
Clinical manifestations associated with neurocysticercosis: a systematic review
Hélène Carabin,Patrick C. Ndimubanzi,Christine M. Budke,Hai Nguyen,Ying-Jun Qian,Linda D. Cowan,Julie A. Stoner,Elizabeth Rainwater,Mary Kathryn Dickey +8 more
TL;DR: The proportion of NCC cases with seizures/epilepsy and the proportion of headaches were consistent across studies, and NCC is a pleomorphic disease linked to a range of manifestations.
Journal ArticleDOI
Neurocysticercosis: A Review
TL;DR: The introduction of cysticidal drugs have shown to reduce the burden of infection in the brain and to improve the clinical course of the disease in most patients and efforts should be directed to eradicate the disease through the implementation of control programs against all the interrelated steps in the life cycle of T. solium.
Journal ArticleDOI
Subarachnoid basal neurocysticercosis: a focus on the most severe form of the disease.
TL;DR: A critical review of the central epidemiological, clinical, diagnostic and therapeutic features of this particular form of the disease, which is still associated with unacceptably high rates of morbidity and mortality.
References
More filters
Journal ArticleDOI
“Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician
Marshal F. Folstein,Marshal F. Folstein,Susan E B Folstein,Susan E B Folstein,Paul R. McHugh,Paul R. McHugh +5 more
TL;DR: A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
A practical method for grading the cognitive state of patients for the clinician
TL;DR: The Mini-Mental State (MMS) as mentioned in this paper is a simplified version of the standard WAIS with eleven questions and requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
Journal ArticleDOI
Research diagnostic criteria: Rationale and reliability.
TL;DR: The development and initial reliability studies of a set of specific diagnostic criteria for a selected group of functional psychiatric disorders, the Research Diagnostic Criteria (RDC), indicate high reliability for diagnostic judgments made using these criteria.
Journal ArticleDOI
O Mini-Exame do Estado Mental em uma população geral: impacto da escolaridade
TL;DR: Education level, classified as illiterate, elementary and middle, was a significant predictor of performance and education-specific reference values for the MMSE are necessary in interpreting individual test results in populations of low educational level, in order to reduce the false positive results.
Journal ArticleDOI
Research diagnostic criteria.
TL;DR: The article by Overall and Hollister in this paper "Comparative Evaluation of Research Diagnostic Criteria for Schizophrenia" troubles us for several reasons, such as the authors do not address the issue of the different purposes of various sets of research diagnostic criteria.
Related Papers (5)
Proposed diagnostic criteria for neurocysticercosis
Neurocysticercosis: A New Classification Based on Active and Inactive Forms: A Study of 753 Cases
An Enzyme-Linked Immunoelectrotransfer Blot Assay and Glycoprotein Antigens for Diagnosing Human Cysticercosis (Taenia solium)
Current Consensus Guidelines for Treatment of Neurocysticercosis
Hector H. Garcia,Carlton A. Evans,Carlton A. Evans,Theodore E. Nash,Osvaldo Massaiti Takayanagui,A. Clinton White,David Botero,Vedantam Rajshekhar,Victor C. W. Tsang,Peter M. Schantz,J. C. Allan,Ana Flisser,Dolores Correa,Elsa Sarti,Jon S. Friedland,S. Manuel Martinez,Armando E. Gonzalez,Robert H. Gilman,Robert H. Gilman,Oscar H. Del Brutto +19 more