Punctate inner choroidopathy: a clinical case report.
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TLDR
An intravitreal injection of bevacizumab was administered in the LE, which resulted in anatomic and visual improvement, and a rare case of unilateral CNV secondary to punctate inner choroidopathy in a young, myopic male is presented.Abstract:
Purpose: To report an uncommon case of a 29-year-old Caucasian male diagnosed with unilateral choroidal neovascularization (CNV) secondary to punctate inner choroidopathy leading to visual impairment. Methods: This is a retrospective and descriptive case report based on data from clinical records, patient observation and analysis of ancillary diagnostic tests. Results: A 29-year-old Caucasian male presented to our emergency department with complaints of decreased central vision in his left eye (LE), detected a few hours before. Bestcorrected visual acuity (BCVA) in the LE was counting fingers at 50 cm and BCVA in the right eye was 20/20. Fundoscopy of the LE evidenced multiple round and yellowish lesions in the macula and nasal to the optic nerve, without intraocular inflammation signs. Optical coherence tomography showed increased retinal thickness with detachment of the neuroepithelium and a slight retinal pigment epithelium detachment. Fluorescein angiography revealed hyperfluorescent lesions with blurred borders in the macula. An intravitreal injection of bevacizumab (1.25 mg/0.05 ml) was administered in the LE, which resulted in anatomic and visual improvement. Conclusion: We present a rare case of unilateral CNV secondary to punctate inner choroidopathy in a young, myopic male.read more
Citations
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Efficacy and safety of conbercept as a primary treatment for choroidal neovascularization secondary to punctate inner choroidopathy.
TL;DR: Intravitreal injection of conbercept significantly improved visual and anatomical outcomes in choroidal neovascularization secondary to punctate inner choroidopathy over a 6-month follow-up period.
Punctate inner choroidopathy: a systematic review.
TL;DR: Clinically relevant data regarding punctate inner choroidopathy, clinical findings and ancillary tests that help in the diagnosis and detection of complications are reviewed.
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Intravitreal anti-VEGF treatment for choroidal neovascularization secondary to punctate inner choroidopathy.
TL;DR: Intravitreal anti-VEGF therapy seems to be safe and effective for PIC-related CNV, a frequent complication of PIC.
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Choroidal Neovascularization Associated with Punctate Inner Choroidopathy: Combination of Intravitreal Anti-VEGF and Systemic Immunosuppressive Therapy.
TL;DR: Combined therapy of immunosuppression with intravitreal anti-VEGF injections can be considered as therapeutic strategy in the management of recurrent CNV associated with PIC.
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Utility of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for an In Vitro Model of Proliferative Vitreoretinopathy.
TL;DR: The role of iPS-RPE in the development of an in vitro model of Proliferative vitreoretinopathy is described, which will provide valuable information regarding cellular wound healing responses specific to RPE and enable the identification of effective therapeutics.
References
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Journal ArticleDOI
Punctate inner choroidopathy.
Robert C. Watzke,Andrew J. Packer,James C. Folk,William E. Benson,Dean B. Burgess,Richard R. Ober +5 more
TL;DR: Ten moderately myopic women had blurred vision, light flashes, or paracentral scotomas associated with small yellow-white lesions of the inner choroid and pigment epithelium that healed into atrophic scars and became progressively more pigmented with time.
Journal ArticleDOI
Visual Prognosis of Multifocal Choroiditis, Punctate Inner Choroidopathy, and the Diffuse Subretinal Fibrosis Syndrome
TL;DR: Most patients with MCP and PIC retained visual acuity of 20/40 or better, while patients with DSF syndrome had a poor prognosis due to fibrosis and atrophy involving the macula.
Journal ArticleDOI
Intravitreal bevacizumab (avastin) for choroidal neovascularization secondary to central serous chorioretinopathy, secondary to punctate inner choroidopathy, or of idiopathic origin.
TL;DR: Intravitreal bevacizumab injections resulted in visual and anatomic improvements in eyes with idiopathic CNV and CNV attributable to central serous chorioretinopathy or punctate inner choroidopathy or PIC.
Journal ArticleDOI
Punctate Inner Choroidopathy: A Survey Analysis of 77 Persons
Adam T. Gerstenblith,Jennifer E. Thorne,Jennifer E. Thorne,Lucia Sobrin,Diana V. Do,Syed Mahmood Shah,C. Stephen Foster,Douglas A. Jabs,Douglas A. Jabs,Quan Dong Nguyen +9 more
TL;DR: The majority of respondents were young, myopic, Caucasian women, who experienced unilateral scotoma and blurred vision as initial symptoms, and the ocular complications choroidal neovascularization and subretinal fibrosis were present in the majority of participants in at least one eye.
Journal ArticleDOI
Subfoveal Choroidal Neovascularization in Punctate Inner Choroidopathy: Surgical Management and Pathologic Findings
Timothy W. Olsen,Antonio Capone,Paul Sternberg,Hans E. Grossniklaus,Daniel F. Martin,Thomas M. Aaberg +5 more
TL;DR: Punctate inner choroidopathyl, multifocal choroidalitis, and multifocal chronic inflammatory disease associated with progressive subretinal fibrosis may all appear quite similar clinically Patients affected with these conditions, which may represent either variants of single disorder or a spectrum of disease, have a similar profile.