Journal ArticleDOI
Racial differences in blood pressure in Evans County, Georgia: relationship to sodium and potassium intake and plasma renin activity.
C.E. Grim,C.E. Grim,F.C. Luft,F.C. Luft,J.Z. Miller,J.Z. Miller,G.R. Meneely,G.R. Meneely,H.D. Battarbee,H.D. Battarbee,Curtis G. Hames,Curtis G. Hames,L.K. Dahl,L.K. Dahl +13 more
TLDR
The higher blood pressures and higher prevalence of hypertension in blacks does not appear to be a function of a greater dietary sodium intake in blacks, but an increased susceptibility to the hypertensinogenic effects of sodium in blacks remains a possibility.About:
This article is published in Journal of Chronic Diseases.The article was published on 1980-01-01. It has received 212 citations till now. The article focuses on the topics: Plasma renin activity & Population.read more
Citations
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Journal ArticleDOI
Sodium and Potassium in the Pathogenesis of Hypertension
TL;DR: This review examines epidemiologic, physiological, and molecular evidence that the interplay between sodium and potassium is central to the development of hypertension and makes recommendations for reducing sodium and increasing potassium in the diet.
Journal ArticleDOI
By how much does dietary salt reduction lower blood pressure? II--Analysis of observational data within populations.
C. D. Frost,Malcolm Law,N J Wald +2 more
TL;DR: The association of blood pressure with sodium intake is substantially larger than is generally appreciated and increases with age and initial blood pressure.
Journal ArticleDOI
Normotensive Salt Sensitivity: Effects of Race and Dietary Potassium
TL;DR: It is demonstrated that in most normotensive black men but not white men, salt sensitivity occurs when dietary potassium is even marginally deficient but is dose-dependently suppressed when dietaryassium is increased within its normal range.
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The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children.
TL;DR: T235 was more frequent, and the level of angiotensinogen was higher in blacks than in whites, which may contribute to the disparity in blood pressure levels of white and black young people.
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Increased blood pressure during potassium depletion in normotensive men
TL;DR: It is concluded that short-term potassium depletion increases blood pressure in healthy, normotensive men and permits further increases in blood pressure after saline loading and no evidence that the hypertensive effect of potassium depletion resulted from changes in either renal hemodynamics or circulating levels of vasoactive hormones.
References
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Effects of chronic excess salt ingestion evidence that genetic factors play an important role in susceptibility to experimental hypertension
TL;DR: Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats, one of these very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet.
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Salt, volume and the prevention of hypertension.
TL;DR: The evidence is very good if not conclusive that reduction of salt in the diet to below 2 g/day would result in the prevention of essential hypertension and its disappearance as a major public health problem.
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High sodium-low potassium environment and hypertension.
TL;DR: When an entire population eats excessively of salt, hypertension will develop among those genetically susceptible, but epidemiologic studies of salt versus blood pressure will not show a relation of salt to hypertension, this is the saturation effect.
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Effects of volume expansion and contraction in normotensive whites, blacks, and subjects of different ages.
TL;DR: The greater prevalence of hypertension in both blacks and older subjects may be related to relatively blunted natriuretic responses when these groups engage in the high sodium-low potassium intake characteristic of the authors' society.